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NCT01817374 · ClinicalTrials.gov registry record · NA
Breast VCEUS to Evaluate Early Response to Neoadjuvant Chemotherapy
A NA study, sponsored by University of Alabama at Birmingham.
- Terminated
- Registry status
- NA
- Development phase
- 6
- Enrollment target
NCT01817374: Clinical Trial NA study, sponsored by University of Alabama at Birmingham.
NCT01817374 is a NA study that was terminated before completion, run by University of Alabama at Birmingham. The registered enrollment target is 6 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01817374, a NA study, was terminated before completion, sponsored by University of Alabama at Birmingham.
- TERMINATED
- Registry status
- NA
- Development phase
- 6 participants
- Enrollment target
Study Summary
1. Evaluate quantitative VCEUS imaging for determining early breast cancer response to neoadjuvant chemotherapy and compare results to co-temporal volume change on grayscale ultrasound and post-treatment mammography findings utilizing final surgical pathology and clinical outcome. 2. Assess incremental benefit of quantitative VCEUS to planar CEUS tumor perfusion measurements and enhancement patterns in predicting tumor response to adjuvant treatment in clinical studies. The contrast agent Definity® is FDA approved for use as a contrast agent during ultrasound (echocardiography) of the heart. Definity® will be used "off-label" (during ultrasound of the breast) in this study. The administration of Definity® during this study will follow total dose guidelines approved by the FDA.
Primary Outcome
Grayscale ultrasound (standard of care) size in millimeters along the longest axis. Range of the grayscale is a minimum of 21.0 millimeters and maximum of 82 millimeters.
Interventions
- DIAGNOSTIC_TEST 2D US grayscale plus quantitative VCEUS
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 6 participants |
| Start Date | 2015-06 |
| Est. Completion | 2016-07 |
| Phase | NA |
Why NCT01817374 stopped before completion
NCT01817374 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 1 intervention - of which 2D US grayscale plus quantitative VCEUS is the first listed.
NCT01817374 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01817374 about?
NCT01817374 is a clinical study titled "Breast VCEUS to Evaluate Early Response to Neoadjuvant Chemotherapy". 1. Evaluate quantitative VCEUS imaging for determining early breast cancer response to neoadjuvant chemotherapy and compare results to co-temporal volume change on grayscale ultrasound and post-treatment mammography findings utilizing final surgical pathology and clinical outcome. 2. Assess incremen...
What is the current status of trial NCT01817374?
This trial is currently terminated. It is a NA study. The enrollment target is 6 participants. The study started on 2015-06. Estimated completion is 2016-07.
What interventions are being tested in trial NCT01817374?
The interventions under investigation include: 2D US grayscale plus quantitative VCEUS (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT01817374?
This trial is sponsored by University of Alabama at Birmingham, which has 1,160 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01817374's enrollment target sits among peer trials
6 1983rd of 2000 higher than 13 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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