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NCT01816880 · ClinicalTrials.gov registry record
Wellderly Immune Antibodies Study, a Sub-Study of Healthy Elderly Active Longevity (HEAL) Cohort
A clinical trial, sponsored by Scripps Translational Science Institute.
- Completed
- Registry status
- 15
- Enrollment target
NCT01816880: Completed study, sponsored by Scripps Translational Science Institute.
NCT01816880 is a clinical trial that has completed, run by Scripps Translational Science Institute. The registered enrollment target is 15 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01816880 has completed, sponsored by Scripps Translational Science Institute.
- COMPLETED
- Registry status
- 15 participants
- Enrollment target
Study Summary
The aim of this sub-study is to determine whether healthy individuals over 90 years of age possess immune cells that are involved in protection from chronic disease. The immune system is well known to produce anti-cancer and other immune cells, called antibodies that can be beneficial to our health. In this study the investigators will evaluate the immune status of the healthy individuals over 90 years of age. The investigators will be focused on studying molecules known to be involved in cholesterol, cancer like those for prostate cancer and breast cancer, inflammatory diseases, and infectious diseases like influenza.
Primary Outcome
We have made phage display libraries from the antibody genes derived from Wellderly B-cells. Remarkably, we could identify specific antibodies against several targets involved in multiple chronic diseases including PCSK9, inflammatory cytokines, and influenza hemaglutinin. We hypothesize that the Wellderly may contain antibodies targeting antigens involved in chronic disease, and that these antibodies may be protective and health-promoting.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2012-06 |
| Est. Completion | 2015-05 |
What the finished NCT01816880 record still lists
NCT01816880 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 15 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT01816880 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01816880 about?
NCT01816880 is a clinical study titled "Wellderly Immune Antibodies Study, a Sub-Study of Healthy Elderly Active Longevity (HEAL) Cohort". The aim of this sub-study is to determine whether healthy individuals over 90 years of age possess immune cells that are involved in protection from chronic disease. The immune system is well known to produce anti-cancer and other immune cells, called antibodies that can be beneficial to our health....
What is the current status of trial NCT01816880?
This trial is currently completed. The enrollment target is 15 participants. The study started on 2012-06. Estimated completion is 2015-05.
Who is sponsoring clinical trial NCT01816880?
This trial is sponsored by Scripps Translational Science Institute, which has 41 total clinical trials registered on ClinicalTrials.gov.
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