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NCT01816776 · ClinicalTrials.gov registry record · NA

Respicardia, Inc. Pivotal Trial of the remedē System

A NA study, sponsored by Respicardia.

Completed
Registry status
NA
Development phase
151
Enrollment target

NCT01816776: Completed NA study, sponsored by Respicardia.

NCT01816776 is a NA study that has completed, run by Respicardia. The registered enrollment target is 151 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (89% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01816776, a NA study, has completed, sponsored by Respicardia.

COMPLETED
Registry status
NA
Development phase
151 participants
Enrollment target

Study Summary

The primary purpose of this prospective, multicenter, randomized trial is to evaluate the safety and effectiveness of therapy delivered by the remedē® system in subjects with moderate to severe central sleep apnea and optimal medical management, compared to outcomes in randomized control subjects receiving optimal medical management and implanted but inactive remedē® systems.

Primary Outcome

Comparison of the proportion of subjects in the Treatment group achieving a 50% or greater reduction in AHI from baseline to 6 months compared to the Control group.

Interventions

  • DEVICE Treatment Group (transvenous stimulation of the phrenic nerve)
  • DEVICE Control Group (Optimal Medical Therapy)

Trial Details

FieldValue
Enrollment Target 151 participants
Start Date 2013-03
Est. Completion 2017-11-07
Phase NA
Respicardia

8 total trials

What the finished NCT01816776 record still lists

NCT01816776 is an interventional study that assigns participants to a tested intervention. The registered 151 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (89% lower).

The record links to 0 conditions, and to 2 interventions - of which Treatment Group (transvenous stimulation of the phrenic nerve) is the first listed.

NCT01816776 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01816776 about?

NCT01816776 is a clinical study titled "Respicardia, Inc. Pivotal Trial of the remedē System". The primary purpose of this prospective, multicenter, randomized trial is to evaluate the safety and effectiveness of therapy delivered by the remedē® system in subjects with moderate to severe central sleep apnea and optimal medical management, compared to outcomes in randomized control subjects re...

What is the current status of trial NCT01816776?

This trial is currently completed. It is a NA study. The enrollment target is 151 participants. The study started on 2013-03. Estimated completion is 2017-11-07.

What interventions are being tested in trial NCT01816776?

The interventions under investigation include: Treatment Group (transvenous stimulation of the phrenic nerve) (DEVICE), Control Group (Optimal Medical Therapy) (DEVICE).

Who is sponsoring clinical trial NCT01816776?

This trial is sponsored by Respicardia, which has 8 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01816776's enrollment target sits among peer trials

151 661st of 2000 higher than 1,340 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01816776, the US trial registry maintained by the National Library of Medicine. NCT01816776 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.