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NCT01814254 · ClinicalTrials.gov registry record

Comparison of Body Hydration State in Hemodialysis Patients

A clinical trial, sponsored by Renal Research Institute.

Terminated
Registry status
67
Enrollment target

NCT01814254 is a clinical trial that was terminated before completion, run by Renal Research Institute. The registered enrollment target is 67 participants.

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The verdict

NCT01814254 was terminated before completion, sponsored by Renal Research Institute.

TERMINATED
Registry status
67 participants
Enrollment target

Study Summary

Estimation of hydration state in dialysis patients is a major challenge in clinical practice. Although many methods have been studied, none have been established yet for clinical routine practice. The investigators have developed a method, using segmental and calf bioimpedance spectroscopy (cBIS) techniques to measure body hydration. The device we used based on the FDA-approved Hydra 4200 (Xitron Technologies, San Diego, CA). The Hydra 4200 was initially developed to measure whole body and segmental body fluid volumes but Hydra is approved only for measuring healthy subjects. The cBIS monitors hydration state by continuously measuring change in resistance and resistivity in the calf during hemodialysis (HD) or it can be used for simple measurement before, during and after dialysis. Preliminary results in clinical studies have shown that optimal hydration state of HD patients may be determined by the calf method. This study aims to compare the Hydra 4200 to two other devices: the FDA approved ZOE (100 kHz) Fluid Status Monitor (Noninvasive Medical Technologies, Inc, Las Vegas) and a modified version ZOE 5 kHz. The modified ZOE monitor (ZOE (5 kHz)) delivers frequency of 5 kHz and 0.8 mA current instead of 100 kHz and 2 mA. The subjects of this study include a group of hemodialysis patients and a group of healthy controls. The healthy controls are used to identify a normal range within the healthy population for each method. Each hemodialysis patient will be studied twice in different hydration state. The study will not change the procedure of the patient's dialysis treatment. Since all devices are based on noninvasive bioimpedance technique, this study has minimal risk.

Trial Details

FieldValue
Enrollment Target 67 participants
Start Date 2011-07
Est. Completion 2013-02

Sponsor

Renal Research Institute

14 total trials

What the Registry Record Tells You About NCT01814254

The ClinicalTrials.gov registry entry for NCT01814254 describes a study currently listed as terminated, categorized as an unspecified phase. The registered enrollment target is 67 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Renal Research Institute, which has 14 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 0 interventions.

NCT01814254 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01814254 about?

NCT01814254 is a clinical study titled "Comparison of Body Hydration State in Hemodialysis Patients". Estimation of hydration state in dialysis patients is a major challenge in clinical practice. Although many methods have been studied, none have been established yet for clinical routine practice. The investigators have developed a method, using segmental and calf bioimpedance spectroscopy (cBIS) t...

What is the current status of trial NCT01814254?

This trial is currently terminated. The enrollment target is 67 participants. The study started on 2011-07. Estimated completion is 2013-02.

Who is sponsoring clinical trial NCT01814254?

This trial is sponsored by Renal Research Institute, which has 14 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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