Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT01804777 · ClinicalTrials.gov registry record · Early Phase 1
Epithelial Sodium Channel (ENaC) as a Novel Mechanism for Hypertension and Volume Expansion in Type 2 Diabetes
A Early Phase 1 study, sponsored by University of New Mexico.
- Terminated
- Registry status
- Early Phase 1
- Development phase
- 9
- Enrollment target
NCT01804777: Clinical Trial Early Phase 1 study, sponsored by University of New Mexico.
NCT01804777 is a Early Phase 1 study that was terminated before completion, run by University of New Mexico. The registered enrollment target is 9 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (83% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01804777, a Early Phase 1 study, was terminated before completion, sponsored by University of New Mexico.
- TERMINATED
- Registry status
- Early Phase 1
- Development phase
- 9 participants
- Enrollment target
Study Summary
The purpose of this study is to determine with the administration of amiloride, observe an enhanced natriuresis, reduction in blood pressure and weight compared to the administration of hydrochlorothiazide in Type 2 Diabetics.
Primary Outcome
Change in clinic systolic BP. This BP measure will be the average of three serial BP measurements taken one minute apart after 5 minutes of sitting quietly.
Interventions
- DRUG Amiloride
- DRUG HCTZ
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9 participants |
| Start Date | 2013-03 |
| Est. Completion | 2014-12 |
| Phase | Early Phase 1 |
Why NCT01804777 stopped before completion
NCT01804777 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 9 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (83% lower).
The record links to 0 conditions, and to 2 interventions - of which Amiloride is the first listed.
NCT01804777 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01804777 about?
NCT01804777 is a clinical study titled "Epithelial Sodium Channel (ENaC) as a Novel Mechanism for Hypertension and Volume Expansion in Type 2 Diabetes". The purpose of this study is to determine with the administration of amiloride, observe an enhanced natriuresis, reduction in blood pressure and weight compared to the administration of hydrochlorothiazide in Type 2 Diabetics.
What is the current status of trial NCT01804777?
This trial is currently terminated. It is a Early Phase 1 study. The enrollment target is 9 participants. The study started on 2013-03. Estimated completion is 2014-12.
What interventions are being tested in trial NCT01804777?
The interventions under investigation include: Amiloride (DRUG), HCTZ (DRUG).
Who is sponsoring clinical trial NCT01804777?
This trial is sponsored by University of New Mexico, which has 168 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01804777's enrollment target sits among peer trials
9 1745th of 2000 higher than 219 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia