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NCT01804140 · ClinicalTrials.gov registry record
A Screening Study to Detect BRAF V600 Mutation-Positive Patients For Enrollment Into Clinical Research Studies of Zelboraf (Vemurafenib)
A clinical trial, sponsored by Genentech.
- Completed
- Registry status
- 662
- Enrollment target
NCT01804140: Completed study, sponsored by Genentech.
NCT01804140 is a clinical trial that has completed, run by Genentech. The registered enrollment target is 662 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01804140 has completed, sponsored by Genentech.
- COMPLETED
- Registry status
- 662 participants
- Enrollment target
Study Summary
This is a screening study to detect BRAF V600 mutation-positive patients for enrollment into clinical research studies of Zelboraf (vemurafenib). Tumor samples will be collected and analyzed from eligible patients with solid tumors (other than metastatic melanoma or papillary thyroid cancer) or multiple myeloma. All institutions with identified patients as defined by this screening protocol will have potential access to the separate vemurafenib protocol MO28072.
Primary Outcome
Formalin-fixed paraffin-embedded (FFPEs) tumor samples (at least 5 serially-cut, unstained, 5 micrometer \[μm\] sections) were collected from eligible participants who consented to participate in the study. FFPE tumor samples were either from archived sections (from the initial diagnosis of cancer) or from fresh biopsies that were performed according to local standards. Tumor samples were then sent to a central laboratory to identify activating BRAF V600 mutations. Identification of mutations wa
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 662 participants |
| Start Date | 2012-12 |
| Est. Completion | 2013-09 |
What the finished NCT01804140 record still lists
NCT01804140 is an observational study that tracks outcomes without assigning an intervention. The registered 662 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT01804140 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01804140 about?
NCT01804140 is a clinical study titled "A Screening Study to Detect BRAF V600 Mutation-Positive Patients For Enrollment Into Clinical Research Studies of Zelboraf (Vemurafenib)". This is a screening study to detect BRAF V600 mutation-positive patients for enrollment into clinical research studies of Zelboraf (vemurafenib). Tumor samples will be collected and analyzed from eligible patients with solid tumors (other than metastatic melanoma or papillary thyroid cancer) or mult...
What is the current status of trial NCT01804140?
This trial is currently completed. The enrollment target is 662 participants. The study started on 2012-12. Estimated completion is 2013-09.
Who is sponsoring clinical trial NCT01804140?
This trial is sponsored by Genentech, which has 332 total clinical trials registered on ClinicalTrials.gov.
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