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NCT01787994 · ClinicalTrials.gov registry record · Phase 1
Redirected MazF-CD4 Autologous T Cells for HIV Gene Therapy
A Phase 1 study, sponsored by University of Pennsylvania.
- Completed
- Registry status
- Phase 1
- Development phase
- 10
- Enrollment target
NCT01787994: Completed Phase 1 study, sponsored by University of Pennsylvania.
NCT01787994 is a Phase 1 study that has completed, run by University of Pennsylvania. The registered enrollment target is 10 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (83% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01787994, a Phase 1 study, has completed, sponsored by University of Pennsylvania.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 10 participants
- Enrollment target
Study Summary
This is an open label, dual cohort study evaluating safety, tolerability and immunogenicity of redirected CD4+ T cells in HIV subjects.
Interventions
- GENETIC Autologous CD4+ T cells genetically modified with a retroviral vector expressing the MazF endoribonuclease gene (MazF-T), given via intravenous infusion.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2012-12 |
| Est. Completion | 2017-07 |
| Phase | Phase 1 |
What the finished NCT01787994 record still lists
NCT01787994 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (83% lower).
The record links to 0 conditions, and to 1 intervention - of which Autologous CD4+ T cells genetically modified with a retroviral vector expressing the MazF endoribonuclease gene (MazF-T), given via intravenous infusion. is the first listed.
NCT01787994 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01787994 about?
NCT01787994 is a clinical study titled "Redirected MazF-CD4 Autologous T Cells for HIV Gene Therapy". This is an open label, dual cohort study evaluating safety, tolerability and immunogenicity of redirected CD4+ T cells in HIV subjects.
What is the current status of trial NCT01787994?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 10 participants. The study started on 2012-12. Estimated completion is 2017-07.
What interventions are being tested in trial NCT01787994?
The interventions under investigation include: Autologous CD4+ T cells genetically modified with a retroviral vector expressing the MazF endoribonuclease gene (MazF-T), given via intravenous infusion. (GENETIC).
Who is sponsoring clinical trial NCT01787994?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01787994's enrollment target sits among peer trials
10 1913th of 2000 higher than 46 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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