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NCT01779167 · ClinicalTrials.gov registry record · Phase 2

Thalidomide, Lenalidomide, and Rituximab for Previously Treated Waldenstrom Macroglobulinemia

A Phase 2 study, sponsored by Weill Medical College of Cornell University.

Terminated
Registry status
Phase 2
Development phase
4
Enrollment target

NCT01779167 is a Phase 2 study that was terminated before completion, run by Weill Medical College of Cornell University. The registered enrollment target is 4 participants.

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The verdict

NCT01779167, a Phase 2 study, was terminated before completion, sponsored by Weill Medical College of Cornell University.

TERMINATED
Registry status
Phase 2
Development phase
4 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate the efficacy and safety of daily alternating thalidomide and lenalidomide plus rituximab (ThRiL) in patients with previously treated Waldenstrom macroglobulunemia (WM). Thalidomide and lenalidomide are drugs that modulate the immune system and have been shown to bring about responses in subjects with WM. However, their use has been limited due to side effects. The investigators hypothesize that alternating doses of thalidomide and lenalidomide may alleviate the side effects while preserving the effectiveness of the therapies.

Interventions

  • DRUG Rituximab
  • DRUG Lenalidomide
  • DRUG Thalidomide

Trial Details

FieldValue
Enrollment Target 4 participants
Start Date 2012-06
Est. Completion 2014-04
Phase Phase 2

What the Registry Record Tells You About NCT01779167

The ClinicalTrials.gov registry entry for NCT01779167 describes a study currently listed as terminated, categorized as Phase 2. The registered enrollment target is 4 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Weill Medical College of Cornell University, which has 701 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Rituximab is the first listed.

NCT01779167 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01779167 about?

NCT01779167 is a clinical study titled "Thalidomide, Lenalidomide, and Rituximab for Previously Treated Waldenstrom Macroglobulinemia". The purpose of this study is to evaluate the efficacy and safety of daily alternating thalidomide and lenalidomide plus rituximab (ThRiL) in patients with previously treated Waldenstrom macroglobulunemia (WM). Thalidomide and lenalidomide are drugs that modulate the immune system and have been shown...

What is the current status of trial NCT01779167?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 4 participants. The study started on 2012-06. Estimated completion is 2014-04.

What interventions are being tested in trial NCT01779167?

The interventions under investigation include: Rituximab (DRUG), Lenalidomide (DRUG), Thalidomide (DRUG).

Who is sponsoring clinical trial NCT01779167?

This trial is sponsored by Weill Medical College of Cornell University, which has 701 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.