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NCT01776307 · ClinicalTrials.gov registry record · Phase 2
A Study of BBI608 in Adult Patients With Advanced Colorectal Cancer
A Phase 2 study, sponsored by Sumitomo Pharma America.
- Completed
- Registry status
- Phase 2
- Development phase
- 200
- Enrollment target
NCT01776307: Completed Phase 2 study, sponsored by Sumitomo Pharma America.
NCT01776307 is a Phase 2 study that has completed, run by Sumitomo Pharma America. The registered enrollment target is 200 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (50% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01776307, a Phase 2 study, has completed, sponsored by Sumitomo Pharma America.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 200 participants
- Enrollment target
Study Summary
This is an open label, multi-center, Phase 2 study of BBI608 in combination with cetuximab, panitumumab or capecitabine in patients with advanced colorectal cancer.
Primary Outcome
Assessment of Disease Control Rate, defined as the proportion of patients with a documented complete response, partial response and stable disease based on RECIST 1.1, in patients with advanced colorectal cancer given napabucasin in combination with cetuximab, panitumumab or capecitabine
Interventions
- DRUG Capecitabine
- DRUG Cetuximab
- DRUG Panitumumab
- DRUG BBI608
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2012-03 |
| Est. Completion | 2020-04 |
| Phase | Phase 2 |
What the finished NCT01776307 record still lists
NCT01776307 is an interventional study that assigns participants to a tested intervention. The registered 200 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (50% higher).
The record links to 0 conditions, and to 4 interventions - of which Capecitabine is the first listed.
NCT01776307 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01776307 about?
NCT01776307 is a clinical study titled "A Study of BBI608 in Adult Patients With Advanced Colorectal Cancer". This is an open label, multi-center, Phase 2 study of BBI608 in combination with cetuximab, panitumumab or capecitabine in patients with advanced colorectal cancer.
What is the current status of trial NCT01776307?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 200 participants. The study started on 2012-03. Estimated completion is 2020-04.
What interventions are being tested in trial NCT01776307?
The interventions under investigation include: Capecitabine (DRUG), Cetuximab (DRUG), Panitumumab (DRUG), BBI608 (DRUG).
Who is sponsoring clinical trial NCT01776307?
This trial is sponsored by Sumitomo Pharma America, which has 168 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01776307's enrollment target sits among peer trials
200 304th of 2000 higher than 1,652 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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