Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT01772719 · ClinicalTrials.gov registry record · NA
Overcoming Chemotherapy Resistance In Refractory Multiple Myeloma With Simvastatin and Zoledronic Acid
A NA study, sponsored by University of Louisville.
- Terminated
- Registry status
- NA
- Development phase
- 7
- Enrollment target
NCT01772719: Clinical Trial NA study, sponsored by University of Louisville.
NCT01772719 is a NA study that was terminated before completion, run by University of Louisville. The registered enrollment target is 7 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01772719, a NA study, was terminated before completion, sponsored by University of Louisville.
- TERMINATED
- Registry status
- NA
- Development phase
- 7 participants
- Enrollment target
Study Summary
The purpose of this study is to examine the effect of simvastatin and zoledronic acid on M-protein and/or free light chains when added to conventional chemotherapy for the treatment of multiple myeloma patients.
Primary Outcome
The effect of simvastatin and zolendronic acid on M-Protein and FLC ratio will be measured 4 weeks after treatment begins, then every 4 weeks until progression of disease.
Interventions
- DRUG Simvastatin and zoledronic acid
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7 participants |
| Start Date | 2012-08 |
| Est. Completion | 2016-11 |
| Phase | NA |
Why NCT01772719 stopped before completion
NCT01772719 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 7 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 1 intervention - of which Simvastatin and zoledronic acid is the first listed.
NCT01772719 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01772719 about?
NCT01772719 is a clinical study titled "Overcoming Chemotherapy Resistance In Refractory Multiple Myeloma With Simvastatin and Zoledronic Acid". The purpose of this study is to examine the effect of simvastatin and zoledronic acid on M-protein and/or free light chains when added to conventional chemotherapy for the treatment of multiple myeloma patients.
What is the current status of trial NCT01772719?
This trial is currently terminated. It is a NA study. The enrollment target is 7 participants. The study started on 2012-08. Estimated completion is 2016-11.
What interventions are being tested in trial NCT01772719?
The interventions under investigation include: Simvastatin and zoledronic acid (DRUG).
Who is sponsoring clinical trial NCT01772719?
This trial is sponsored by University of Louisville, which has 217 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01772719's enrollment target sits among peer trials
7 1982nd of 2000 higher than 18 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia