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NCT01759875 · ClinicalTrials.gov registry record · Phase 1

Effects of Gastric pH on the Pharmacokinetics of Atazanavir

A Phase 1 study, sponsored by University of California, San Francisco.

Completed
Registry status
Phase 1
Development phase
8
Enrollment target

NCT01759875 is a Phase 1 study that has completed, run by University of California, San Francisco. The registered enrollment target is 8 participants.

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The verdict

NCT01759875, a Phase 1 study, has completed, sponsored by University of California, San Francisco.

COMPLETED
Registry status
Phase 1
Development phase
8 participants
Enrollment target

Study Summary

The goal of this study is to evaluate the ability of a natural supplement (betaine hydrochloride) to affect the absorption of atazanavir in healthy volunteers. The investigators predict that betaine hydrochloride will increase the absorption of atazanavir in volunteers pre-treated with proton-pump inhibitors (PPIs).

Interventions

  • DRUG Ritonavir-boosted Atazanavir
  • DRUG Ritonavir-boosted Atazanavir plus Rabeprazole
  • DRUG Ritonavir-boosted Atazanavir plus Rabeprazole AND Betaine Hydrochloride

Trial Details

FieldValue
Enrollment Target 8 participants
Start Date 2013-01
Est. Completion 2014-01
Phase Phase 1

What the Registry Record Tells You About NCT01759875

The ClinicalTrials.gov registry entry for NCT01759875 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 8 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, San Francisco, which has 1,713 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Ritonavir-boosted Atazanavir is the first listed.

NCT01759875 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01759875 about?

NCT01759875 is a clinical study titled "Effects of Gastric pH on the Pharmacokinetics of Atazanavir". The goal of this study is to evaluate the ability of a natural supplement (betaine hydrochloride) to affect the absorption of atazanavir in healthy volunteers. The investigators predict that betaine hydrochloride will increase the absorption of atazanavir in volunteers pre-treated with proton-pump i...

What is the current status of trial NCT01759875?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 8 participants. The study started on 2013-01. Estimated completion is 2014-01.

What interventions are being tested in trial NCT01759875?

The interventions under investigation include: Ritonavir-boosted Atazanavir (DRUG), Ritonavir-boosted Atazanavir plus Rabeprazole (DRUG), Ritonavir-boosted Atazanavir plus Rabeprazole AND Betaine Hydrochloride (DRUG).

Who is sponsoring clinical trial NCT01759875?

This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.