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NCT01757340 · ClinicalTrials.gov registry record · NA
Calorie Restriction With Leucine Supplementation
A NA study, sponsored by Washington University School of Medicine.
- Completed
- Registry status
- NA
- Development phase
- 43
- Enrollment target
NCT01757340: Completed NA study, sponsored by Washington University School of Medicine.
NCT01757340 is a NA study that has completed, run by Washington University School of Medicine. The registered enrollment target is 43 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01757340, a NA study, has completed, sponsored by Washington University School of Medicine.
- COMPLETED
- Registry status
- NA
- Development phase
- 43 participants
- Enrollment target
Study Summary
The purpose of this study is to determine whether consuming additional leucine during calorie restriction induced weight loss has beneficial or harmful effects on multi-organ (liver, muscle, adipose tissue) insulin sensitivity, colonocyte proliferation rates, the gut microbiome, muscle mass and function, and bone mineral density in obese, postmenopausal women.
Primary Outcome
We will measure total appendicular skeletal muscle mass by using dual-energy X-ray absorptiometry (DXA) and thigh muscle volume by magnetic resonance imaging (MRI)
Interventions
- BEHAVIORAL Weight loss with normal protein and leucine intake
- BEHAVIORAL Weight loss with protein/leucine supplementation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 43 participants |
| Start Date | 2012-09 |
| Est. Completion | 2017-03 |
| Phase | NA |
What the finished NCT01757340 record still lists
NCT01757340 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 43 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 2 interventions - of which Weight loss with normal protein and leucine intake is the first listed.
NCT01757340 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01757340 about?
NCT01757340 is a clinical study titled "Calorie Restriction With Leucine Supplementation". The purpose of this study is to determine whether consuming additional leucine during calorie restriction induced weight loss has beneficial or harmful effects on multi-organ (liver, muscle, adipose tissue) insulin sensitivity, colonocyte proliferation rates, the gut microbiome, muscle mass and func...
What is the current status of trial NCT01757340?
This trial is currently completed. It is a NA study. The enrollment target is 43 participants. The study started on 2012-09. Estimated completion is 2017-03.
What interventions are being tested in trial NCT01757340?
The interventions under investigation include: Weight loss with normal protein and leucine intake (BEHAVIORAL), Weight loss with protein/leucine supplementation (BEHAVIORAL).
Who is sponsoring clinical trial NCT01757340?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01757340's enrollment target sits among peer trials
43 1435th of 2000 higher than 565 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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