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NCT01755234 · ClinicalTrials.gov registry record · Phase 4

Propofol Versus Sevoflurane Recovery After Gynecological Surgery

A Phase 4 study, sponsored by Northwestern University.

Completed
Registry status
Phase 4
Development phase
90
Enrollment target

NCT01755234 is a Phase 4 study that has completed, run by Northwestern University. The registered enrollment target is 90 participants.

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The verdict

NCT01755234, a Phase 4 study, has completed, sponsored by Northwestern University.

COMPLETED
Registry status
Phase 4
Development phase
90 participants
Enrollment target

Study Summary

80% of 25 million American who undergo surgery describe moderate to severe pain. The use of multimodal analgesic techniques can attenuate patient's postoperative pain and several different medication have been found to be effective. Pain can significantly affect patient's quality of recovery after surgery. Volatile anesthetics can increase sensitivity to pain at the low concentrations present on emergence from anesthesia. Propofol may have analgesic effect at sedative doses. The effects of propofol,when used for anesthesia maintenance, on postoperative pain have demonstrated controversial results with some investigators showing a potential benefit whereas others have not shown any benefit. Propofol for maintenance of anesthesia has been advocated as an strategy for high risk patients even though it has shown controversial results on reduction of Post operative nausea and vomiting. A comparison of propofol vs.volatile anesthetic in regards to the time required by patients to meet discharge criteria has also shown conflicting results.The QOR 40 is a validated instrument that has been specifically developed to evaluate patients recovery after anesthesia and surgery. The purpose of this study is to compare the effects of maintenance of anesthesia with two agents (Propofol and Sevoflurane) on quality of recovery after ambulatory surgery Significance: the results of this study can lead to the discovery of an anesthesia technique that is associated with a better recovery for patients after ambulatory surgery. Research question is: do patients anesthetized with propofol have a better quality of recovery after ambulatory anesthesia than patients anesthetized with Sevoflurane? The hypothesis: patients anesthetized with propofol will have better quality of recovery than patients anesthetized with Sevoflurane after ambulatory surgery.

Interventions

  • DRUG Sevoflurane
  • DRUG Propofol

Trial Details

FieldValue
Enrollment Target 90 participants
Start Date 2012-11
Est. Completion 2014-04
Phase Phase 4

Sponsor

Northwestern University

1,209 total trials

What the Registry Record Tells You About NCT01755234

The ClinicalTrials.gov registry entry for NCT01755234 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 90 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Northwestern University, which has 1,209 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Sevoflurane is the first listed.

NCT01755234 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01755234 about?

NCT01755234 is a clinical study titled "Propofol Versus Sevoflurane Recovery After Gynecological Surgery". 80% of 25 million American who undergo surgery describe moderate to severe pain. The use of multimodal analgesic techniques can attenuate patient's postoperative pain and several different medication have been found to be effective. Pain can significantly affect patient's quality of recovery after s...

What is the current status of trial NCT01755234?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 90 participants. The study started on 2012-11. Estimated completion is 2014-04.

What interventions are being tested in trial NCT01755234?

The interventions under investigation include: Sevoflurane (DRUG), Propofol (DRUG).

Who is sponsoring clinical trial NCT01755234?

This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.