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NCT01748045 · ClinicalTrials.gov registry record · Phase 2
Study of Inhaled Nitric Oxide (iNO) and Respiratory Outcomes in Late Preterm Infants
A Phase 2 study, sponsored by Tufts Medical Center.
- Terminated
- Registry status
- Phase 2
- Development phase
- 3
- Enrollment target
NCT01748045: Clinical Trial Phase 2 study, sponsored by Tufts Medical Center.
NCT01748045 is a Phase 2 study that was terminated before completion, run by Tufts Medical Center. The registered enrollment target is 3 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01748045, a Phase 2 study, was terminated before completion, sponsored by Tufts Medical Center.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 3 participants
- Enrollment target
Study Summary
The aim of this study is to determine if inhaled nitric oxide will improve short and long term respiratory outcomes in preterm infants. Infants born at a gestational age of 30-36 weeks and who require breathing support with high flow nasal cannula, nasal continuous positive airway pressure, or nasal intermittent positive pressure will be randomized to receive either inhaled nitric oxide or placebo. The dose will then be decreased per protocol until all respiratory support has been discontinued. Infants will be followed to evaluate safety and efficacy of non-invasive iNO delivery, up to 12 months corrected gestational age.
Interventions
- DRUG inhaled nitric oxide
- DRUG Placebo Comparator - nitrogen gas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3 participants |
| Start Date | 2013-03 |
| Est. Completion | 2014-07 |
| Phase | Phase 2 |
Why NCT01748045 stopped before completion
NCT01748045 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 3 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which inhaled nitric oxide is the first listed.
NCT01748045 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01748045 about?
NCT01748045 is a clinical study titled "Study of Inhaled Nitric Oxide (iNO) and Respiratory Outcomes in Late Preterm Infants". The aim of this study is to determine if inhaled nitric oxide will improve short and long term respiratory outcomes in preterm infants. Infants born at a gestational age of 30-36 weeks and who require breathing support with high flow nasal cannula, nasal continuous positive airway pressure, or nasal...
What is the current status of trial NCT01748045?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 3 participants. The study started on 2013-03. Estimated completion is 2014-07.
What interventions are being tested in trial NCT01748045?
The interventions under investigation include: inhaled nitric oxide (DRUG), Placebo Comparator - nitrogen gas (DRUG).
Who is sponsoring clinical trial NCT01748045?
This trial is sponsored by Tufts Medical Center, which has 169 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01748045's enrollment target sits among peer trials
3 2001st of 2000 the lowest of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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