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NCT01747538 · ClinicalTrials.gov registry record · Phase 3

Safety and Efficacy Study of Gevokizumab to Treat Non-infectious Uveitis Controlled With Systemic Treatment

A Phase 3 study, sponsored by Xoma (US).

Terminated
Registry status
Phase 3
Development phase
281
Enrollment target

NCT01747538: Clinical Trial Phase 3 study, sponsored by Xoma (US).

NCT01747538 is a Phase 3 study that was terminated before completion, run by Xoma (US). The registered enrollment target is 281 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (64% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01747538, a Phase 3 study, was terminated before completion, sponsored by Xoma (US).

TERMINATED
Registry status
Phase 3
Development phase
281 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate the efficacy of gevokizumab in reducing the risk of recurrent uveitic disease in subjects with non-infectious uveitis whose disease is currently controlled with systemic treatment.

Interventions

  • DRUG Placebo
  • DRUG Dose 2 gevokizumab
  • DRUG Dose 1 gevokizumab

Trial Details

FieldValue
Enrollment Target 281 participants
Start Date 2012-10
Phase Phase 3
Xoma (US)

20 total trials

Why NCT01747538 stopped before completion

NCT01747538 is an interventional study that assigns participants to a tested intervention. The registered 281 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (64% lower).

The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.

NCT01747538 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01747538 about?

NCT01747538 is a clinical study titled "Safety and Efficacy Study of Gevokizumab to Treat Non-infectious Uveitis Controlled With Systemic Treatment". The purpose of this study is to evaluate the efficacy of gevokizumab in reducing the risk of recurrent uveitic disease in subjects with non-infectious uveitis whose disease is currently controlled with systemic treatment.

What is the current status of trial NCT01747538?

This trial is currently terminated. It is a Phase 3 study. The enrollment target is 281 participants. The study started on 2012-10.

What interventions are being tested in trial NCT01747538?

The interventions under investigation include: Placebo (DRUG), Dose 2 gevokizumab (DRUG), Dose 1 gevokizumab (DRUG).

Who is sponsoring clinical trial NCT01747538?

This trial is sponsored by Xoma (US), which has 20 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01747538's enrollment target sits among peer trials

281 1194th of 2000 higher than 806 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01747538, the US trial registry maintained by the National Library of Medicine. NCT01747538 (mid enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.