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NCT01743157 · ClinicalTrials.gov registry record · Phase 1

Biochemotherapy and Bevacizumab Followed by Consolidation Therapy With Ipilimumab for Metastatic Melanoma

A Phase 1 study, sponsored by California Pacific Medical Center Research Institute.

Completed
Registry status
Phase 1
Development phase
24
Enrollment target

NCT01743157: Completed Phase 1 study, sponsored by California Pacific Medical Center Research Institute.

NCT01743157 is a Phase 1 study that has completed, run by California Pacific Medical Center Research Institute. The registered enrollment target is 24 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (60% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01743157, a Phase 1 study, has completed, sponsored by California Pacific Medical Center Research Institute.

COMPLETED
Registry status
Phase 1
Development phase
24 participants
Enrollment target

Study Summary

A phase I-II study of treatment of metastatic melanoma using induction therapy with Biochemotherapy plus Bevacizumab followed by consolidation therapy with Ipilimumab (BBI).

Primary Outcome

Determine the incidence of grade 4 bevacizumab-related toxicities and grade 3 proteinuria when bevacizumab is given with biochemotherapy to patients with metastatic melanoma for up to 3 years.

Interventions

  • DRUG Biochemo + bevacizumab then ipilimumab

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2010-12
Est. Completion 2013-05
Phase Phase 1

What the finished NCT01743157 record still lists

NCT01743157 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (60% lower).

The record links to 0 conditions, and to 1 intervention - of which Biochemo + bevacizumab then ipilimumab is the first listed.

NCT01743157 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01743157 about?

NCT01743157 is a clinical study titled "Biochemotherapy and Bevacizumab Followed by Consolidation Therapy With Ipilimumab for Metastatic Melanoma". A phase I-II study of treatment of metastatic melanoma using induction therapy with Biochemotherapy plus Bevacizumab followed by consolidation therapy with Ipilimumab (BBI).

What is the current status of trial NCT01743157?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2010-12. Estimated completion is 2013-05.

What interventions are being tested in trial NCT01743157?

The interventions under investigation include: Biochemo + bevacizumab then ipilimumab (DRUG).

Who is sponsoring clinical trial NCT01743157?

This trial is sponsored by California Pacific Medical Center Research Institute, which has 29 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01743157's enrollment target sits among peer trials

24 1520th of 2000 higher than 405 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01743157, the US trial registry maintained by the National Library of Medicine. NCT01743157 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.