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NCT01741766 · ClinicalTrials.gov registry record · NA

The Effects of Stretching Training on Arterial Function and Autonomic Control

A NA study, sponsored by Florida State University.

Completed
Registry status
NA
Development phase
30
Enrollment target

NCT01741766: Completed NA study, sponsored by Florida State University.

NCT01741766 is a NA study that has completed, run by Florida State University. The registered enrollment target is 30 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01741766, a NA study, has completed, sponsored by Florida State University.

COMPLETED
Registry status
NA
Development phase
30 participants
Enrollment target

Study Summary

Hypertension is a major risk factor for cardiovascular disease. Hypertension and abdominal obesity are associated with dysfunction of the main mechanisms of cardiovascular regulation, the autonomic nervous system and the vascular endothelium. Increased sympathetic activity and endothelial dysfunction are associated with increased arterial stiffness, which is an independent risk factor for the development of hypertension and other cardiovascular diseases. The recommended intervention for controlling BP in pre- and stage 1- hypertensive individuals is lifestyle modifications such as exercise, and not drug therapy.Although aerobic and resistance exercise has been shown to be beneficial for the cardiovascular system, special populations such as the elderly and obese may have physical and/or musculoskeletal limitations which may limit their participation in these exercise modalities. Stretching is a form of exercise that is widely recommended for injury prevention. Among the benefits of stretching are an increased flexibility, enhanced muscular coordination, stress relief, improved range of motion and an improved posture. Previous studies have shown stretching training to increase arterial compliance and acutely increase sympathetic nerve activity. In addition, low flexibility levels have been found to be associated with arterial stiffness. Given that stretching of skeletal muscle causes an increase in sympathetic nerve activity; repetitive stimulation of sympathetic activity induced by habitual stretching, might chronically reduce resting sympathetic activity. The reduction in sympathetic activity might result in a decrease of arterial stiffness and blood pressure. The investigators hypothesis is that 8 weeks of stretching training would reduce arterial stiffness, blood pressure and sympathetic activity in obese women. The investigators also hypothesize that the improved arterial function with stretching would be associated with increases in flexibility levels.

Primary Outcome

Non-invasive measures of brachial and aortic blood pressure

Interventions

  • OTHER Stretching Training

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2011-05
Est. Completion 2011-12
Phase NA
Florida State University

219 total trials

What the finished NCT01741766 record still lists

NCT01741766 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).

The record links to 0 conditions, and to 1 intervention - of which Stretching Training is the first listed.

NCT01741766 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01741766 about?

NCT01741766 is a clinical study titled "The Effects of Stretching Training on Arterial Function and Autonomic Control". Hypertension is a major risk factor for cardiovascular disease. Hypertension and abdominal obesity are associated with dysfunction of the main mechanisms of cardiovascular regulation, the autonomic nervous system and the vascular endothelium. Increased sympathetic activity and endothelial dysfunctio...

What is the current status of trial NCT01741766?

This trial is currently completed. It is a NA study. The enrollment target is 30 participants. The study started on 2011-05. Estimated completion is 2011-12.

What interventions are being tested in trial NCT01741766?

The interventions under investigation include: Stretching Training (OTHER).

Who is sponsoring clinical trial NCT01741766?

This trial is sponsored by Florida State University, which has 219 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01741766's enrollment target sits among peer trials

30 1593rd of 2000 higher than 299 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01741766, the US trial registry maintained by the National Library of Medicine. NCT01741766 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.