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NCT01739439 · ClinicalTrials.gov registry record · Phase 1

Chemoradiation and Radiosurgery Boost in Treating Patients With Locally Advance Pancreatic Cancer That May or May Not be Removed by Surgery

A Phase 1 study, sponsored by Fox Chase Cancer Center.

Terminated
Registry status
Phase 1
Development phase
6
Enrollment target

NCT01739439: Clinical Trial Phase 1 study, sponsored by Fox Chase Cancer Center.

NCT01739439 is a Phase 1 study that was terminated before completion, run by Fox Chase Cancer Center. The registered enrollment target is 6 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01739439, a Phase 1 study, was terminated before completion, sponsored by Fox Chase Cancer Center.

TERMINATED
Registry status
Phase 1
Development phase
6 participants
Enrollment target

Study Summary

This phase I trial studies the side effects and best dose of radiosurgery boost following chemoradiation in treating patients with locally advanced pancreatic cancer that may or may not be removed by surgery. Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays to kill tumor cells. Radiosurgery can send x-rays directly to the tumor and cause less damage to normal tissue. Giving chemotherapy and radiation therapy together with radiosurgery may kill more tumor cells and allow doctors to save the part of the body where the cancer started

Interventions

  • RADIATION intensity-modulated radiation therapy
  • RADIATION radiosurgery
  • PROCEDURE diffusion-weighted magnetic resonance imaging
  • DRUG gemcitabine hydrochloride
  • RADIATION hyperfractionated radiation therapy

Trial Details

FieldValue
Enrollment Target 6 participants
Start Date 2013-05
Est. Completion 2015-12-01
Phase Phase 1
Fox Chase Cancer Center

183 total trials

Why NCT01739439 stopped before completion

NCT01739439 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (90% lower).

The record links to 0 conditions, and to 5 interventions - of which intensity-modulated radiation therapy is the first listed.

NCT01739439 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01739439 about?

NCT01739439 is a clinical study titled "Chemoradiation and Radiosurgery Boost in Treating Patients With Locally Advance Pancreatic Cancer That May or May Not be Removed by Surgery". This phase I trial studies the side effects and best dose of radiosurgery boost following chemoradiation in treating patients with locally advanced pancreatic cancer that may or may not be removed by surgery. Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either...

What is the current status of trial NCT01739439?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 6 participants. The study started on 2013-05. Estimated completion is 2015-12-01.

What interventions are being tested in trial NCT01739439?

The interventions under investigation include: intensity-modulated radiation therapy (RADIATION), radiosurgery (RADIATION), diffusion-weighted magnetic resonance imaging (PROCEDURE), gemcitabine hydrochloride (DRUG), hyperfractionated radiation therapy (RADIATION).

Who is sponsoring clinical trial NCT01739439?

This trial is sponsored by Fox Chase Cancer Center, which has 183 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01739439's enrollment target sits among peer trials

6 1974th of 2000 higher than 12 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01739439, the US trial registry maintained by the National Library of Medicine. NCT01739439 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.