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NCT01731041 · ClinicalTrials.gov registry record · NA
Impact of Ticagrelor Re-load on Pharmacodynamic Profiles
A NA study, sponsored by University of Florida.
- Completed
- Registry status
- NA
- Development phase
- 60
- Enrollment target
NCT01731041: Completed NA study, sponsored by University of Florida.
NCT01731041 is a NA study that has completed, run by University of Florida. The registered enrollment target is 60 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01731041, a NA study, has completed, sponsored by University of Florida.
- COMPLETED
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
Study Summary
Platelets are parts of your blood that stick together to help form a clot. The stickier your platelets are, the greater your chance of having a heart attack. A clot in the wrong place can lead to a heart attack or stroke. Ticagrelor (Brilinta) keeps platelets from sticking together and it helps people from having a heart attack. The American College of Cardiology has recommended a combination of aspirin and Brilinta as one of the best treatments for the prevention of heart attacks, and death in patients who have had a heart attack or coronary stents. However, it is unknown if Brilinta may improve its work to keep platelets from sticking together giving a loading dose in patients already treated with Brilinta. A loading dose is a one-time increased dose of the same drug. The purpose of this study is to demonstrate whether the platelets of patients treated with Brilinta become less sticky when Brilinta is re-loaded.
Primary Outcome
The primary end-point of the study is the comparison in the platelet reactivity index (PRI%) determined by vasodilator-stimulated phosphoprotein (VASP) between baseline and 4-hour after dosing in each arm of treatment
Interventions
- DRUG Ticagrelor 90mg
- DRUG Ticagrelor 180mg
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2013-01 |
| Est. Completion | 2014-06 |
| Phase | NA |
What the finished NCT01731041 record still lists
NCT01731041 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 2 interventions - of which Ticagrelor 90mg is the first listed.
NCT01731041 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01731041 about?
NCT01731041 is a clinical study titled "Impact of Ticagrelor Re-load on Pharmacodynamic Profiles". Platelets are parts of your blood that stick together to help form a clot. The stickier your platelets are, the greater your chance of having a heart attack. A clot in the wrong place can lead to a heart attack or stroke. Ticagrelor (Brilinta) keeps platelets from sticking together and it helps peop...
What is the current status of trial NCT01731041?
This trial is currently completed. It is a NA study. The enrollment target is 60 participants. The study started on 2013-01. Estimated completion is 2014-06.
What interventions are being tested in trial NCT01731041?
The interventions under investigation include: Ticagrelor 90mg (DRUG), Ticagrelor 180mg (DRUG).
Who is sponsoring clinical trial NCT01731041?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01731041's enrollment target sits among peer trials
60 1164th of 2000 higher than 745 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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