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NCT01721447 · ClinicalTrials.gov registry record · Phase 4
Efficacy of Optison Echo Contrast to Detect Thrombus in Left Atrial Appendage
A Phase 4 study, sponsored by University of Utah.
- Completed
- Registry status
- Phase 4
- Development phase
- 100
- Enrollment target
NCT01721447: Completed Phase 4 study, sponsored by University of Utah.
NCT01721447 is a Phase 4 study that has completed, run by University of Utah. The registered enrollment target is 100 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (81% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01721447, a Phase 4 study, has completed, sponsored by University of Utah.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 100 participants
- Enrollment target
Study Summary
The investigators intend to determine if using Optison echocardiography contrast increases sensitivity and specificity of detecting left atrial appendage thrombus in transesophageal echocardiography studies as opposed to standard 2D and 3D TEE imaging without the use of echo contrast.
Primary Outcome
Confidence among echo readers to determine presence or absence of left atrial appendage thrombus before and after injection of Optison contrast agent. Percent confidence was calculated from a subjective assessment made by each reader after viewing the echo images. A six-point scale was used by the readers to grade the subjective assessment of their confidence in detecting thrombus; a score of 0 representing 0% (no confidence) up to a score of 5 representing 100% (total confidence) that the inter
Interventions
- DRUG Optison echocardiography contrast agent
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2013-06 |
| Est. Completion | 2018-05 |
| Phase | Phase 4 |
What the finished NCT01721447 record still lists
NCT01721447 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (81% lower).
The record links to 0 conditions, and to 1 intervention - of which Optison echocardiography contrast agent is the first listed.
NCT01721447 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01721447 about?
NCT01721447 is a clinical study titled "Efficacy of Optison Echo Contrast to Detect Thrombus in Left Atrial Appendage". The investigators intend to determine if using Optison echocardiography contrast increases sensitivity and specificity of detecting left atrial appendage thrombus in transesophageal echocardiography studies as opposed to standard 2D and 3D TEE imaging without the use of echo contrast.
What is the current status of trial NCT01721447?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 100 participants. The study started on 2013-06. Estimated completion is 2018-05.
What interventions are being tested in trial NCT01721447?
The interventions under investigation include: Optison echocardiography contrast agent (DRUG).
Who is sponsoring clinical trial NCT01721447?
This trial is sponsored by University of Utah, which has 818 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01721447's enrollment target sits among peer trials
100 770th of 2000 higher than 1,148 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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