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NCT01718990 · ClinicalTrials.gov registry record

Biomarker Discovery for Novel Drug Development in Idiopathic Pulmonary Fibrosis

A clinical trial, sponsored by University of California, San Francisco.

Completed
Registry status
110
Enrollment target

NCT01718990: Completed study, sponsored by University of California, San Francisco.

NCT01718990 is a clinical trial that has completed, run by University of California, San Francisco. The registered enrollment target is 110 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01718990 has completed, sponsored by University of California, San Francisco.

COMPLETED
Registry status
110 participants
Enrollment target

Study Summary

Drug discovery can take many years especially since most studies to measure effectiveness depend on clinical outcomes like pulmonary function tests and hospitalizations. This is an observational study designed to collect information, blood, and bronchoalveolar lavage fluid in people who have IPF and those who do not. The people who have IPF will be followed for 12 months to collect more biological samples and record clinically relevant information. The goal of this study is to identify new molecular markers that are measurable and reliable in people who have IPF. It is hoped that these markers can be used in future drug studies to significantly speed up the process of finding drugs that help.

Primary Outcome

We anticipate that we will successfully enroll 60 subjects with IPF in a 12 month longitudinal cohort study and provide biological samples (Bronchiolavage (BAL), alveolar macrophages, and blood) to Projects 1-3 for use in identifying mechanistically-informative markers of alveolar epithelial cell ER stress, αvβ6-mediated TGFβ activation, and EMT. We expect that levels of some of these mechanistic markers will be measurable in patient samples, and may be differentially present in IPF compared to

Trial Details

FieldValue
Enrollment Target 110 participants
Start Date 2012-10
Est. Completion 2018-12-31

What the finished NCT01718990 record still lists

NCT01718990 is an observational study that tracks outcomes without assigning an intervention. The registered 110 participants enrollment target is mid-sized for trials with a published cap.

The record links to 0 conditions, and to 0 interventions.

NCT01718990 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01718990 about?

NCT01718990 is a clinical study titled "Biomarker Discovery for Novel Drug Development in Idiopathic Pulmonary Fibrosis". Drug discovery can take many years especially since most studies to measure effectiveness depend on clinical outcomes like pulmonary function tests and hospitalizations. This is an observational study designed to collect information, blood, and bronchoalveolar lavage fluid in people who have IPF an...

What is the current status of trial NCT01718990?

This trial is currently completed. The enrollment target is 110 participants. The study started on 2012-10. Estimated completion is 2018-12-31.

Who is sponsoring clinical trial NCT01718990?

This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.

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Source: ClinicalTrials.gov NCT01718990, the US trial registry maintained by the National Library of Medicine. NCT01718990 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.