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NCT01717859 · ClinicalTrials.gov registry record · Phase 4
Musculoskeletal Ultrasound in Predicting Early Dose Titration With Tocilizumab
A Phase 4 study, sponsored by University of California, Los Angeles.
- Completed
- Registry status
- Phase 4
- Development phase
- 74
- Enrollment target
NCT01717859: Completed Phase 4 study, sponsored by University of California, Los Angeles.
NCT01717859 is a Phase 4 study that has completed, run by University of California, Los Angeles. The registered enrollment target is 74 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (86% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01717859, a Phase 4 study, has completed, sponsored by University of California, Los Angeles.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 74 participants
- Enrollment target
Study Summary
The purpose of this research study is to determine if a change in inflammation or baseline inflammation seen on the ultrasound is a good indicator of how rheumatoid arthritis patients respond to TCZ 4mg/kg and whether early prediction of dose escalation is possible by utilizing ultrasound inflammatory measures.
Primary Outcome
34 joints will be evaluated using a 0 to 3 point scale for each joint. Power Doppler synovitis score is the sum of all the joint scores. Change scores are calculated by subtracting Baseline minus 3 Month Power Doppler scores. This scale is called the Power Doppler Synovitis Score (PDUS). It ranges from 0 to 102. Scores of 0 indicate the least amount of inflammation of the joint while scores of 3 indicate the most amount of inflammation. Therefore, a higher value of the total score for PDUS repr
Interventions
- DRUG Tocilizumab
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 74 participants |
| Start Date | 2014-09 |
| Est. Completion | 2017-04 |
| Phase | Phase 4 |
What the finished NCT01717859 record still lists
NCT01717859 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 74 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (86% lower).
The record links to 0 conditions, and to 1 intervention - of which Tocilizumab is the first listed.
NCT01717859 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01717859 about?
NCT01717859 is a clinical study titled "Musculoskeletal Ultrasound in Predicting Early Dose Titration With Tocilizumab". The purpose of this research study is to determine if a change in inflammation or baseline inflammation seen on the ultrasound is a good indicator of how rheumatoid arthritis patients respond to TCZ 4mg/kg and whether early prediction of dose escalation is possible by utilizing ultrasound inflammato...
What is the current status of trial NCT01717859?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 74 participants. The study started on 2014-09. Estimated completion is 2017-04.
What interventions are being tested in trial NCT01717859?
The interventions under investigation include: Tocilizumab (DRUG).
Who is sponsoring clinical trial NCT01717859?
This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01717859's enrollment target sits among peer trials
74 1027th of 2000 higher than 968 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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