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NCT01711970 · ClinicalTrials.gov registry record · Phase 1

A Phase I/II Trial of VB-111 and Paclitaxel for Recurrent Platinum-Resistant Müllerian Cancer

A Phase 1 study, sponsored by Vascular Biogenics Ltd. operating as VBL Therapeutics.

Completed
Registry status
Phase 1
Development phase
38
Enrollment target

NCT01711970: Completed Phase 1 study, sponsored by Vascular Biogenics Ltd. operating as VBL Therapeutics.

NCT01711970 is a Phase 1 study that has completed, run by Vascular Biogenics Ltd. operating as VBL Therapeutics. The registered enrollment target is 38 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (37% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01711970, a Phase 1 study, has completed, sponsored by Vascular Biogenics Ltd. operating as VBL Therapeutics.

COMPLETED
Registry status
Phase 1
Development phase
38 participants
Enrollment target

Study Summary

This is a prospective, open label, dose escalating, Phase I/II study, measuring mainly the safety and tolerability of the combination of intravenous administration of VB-111 and paclitaxel in patients with platinum resistant ovarian cancer.

Primary Outcome

Define toxicities of a limited number of doses of combination VB-111 and weekly paclitaxel spanning anticipated effective doses.

Interventions

  • DRUG Paclitaxel

Trial Details

FieldValue
Enrollment Target 38 participants
Start Date 2012-11
Est. Completion 2017-05-03
Phase Phase 1

What the finished NCT01711970 record still lists

NCT01711970 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 38 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (37% lower).

The record links to 0 conditions, and to 1 intervention - of which Paclitaxel is the first listed.

NCT01711970 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01711970 about?

NCT01711970 is a clinical study titled "A Phase I/II Trial of VB-111 and Paclitaxel for Recurrent Platinum-Resistant Müllerian Cancer". This is a prospective, open label, dose escalating, Phase I/II study, measuring mainly the safety and tolerability of the combination of intravenous administration of VB-111 and paclitaxel in patients with platinum resistant ovarian cancer.

What is the current status of trial NCT01711970?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 38 participants. The study started on 2012-11. Estimated completion is 2017-05-03.

What interventions are being tested in trial NCT01711970?

The interventions under investigation include: Paclitaxel (DRUG).

Who is sponsoring clinical trial NCT01711970?

This trial is sponsored by Vascular Biogenics Ltd. operating as VBL Therapeutics, which has 6 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01711970's enrollment target sits among peer trials

38 1197th of 2000 higher than 797 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01711970, the US trial registry maintained by the National Library of Medicine. NCT01711970 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.