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NCT01708629 · ClinicalTrials.gov registry record · Phase 3

Efficacy and Safety of Brodalumab Compared With Placebo and Ustekinumab in Moderate to Severe Plaque Psoriasis Subjects

A Phase 3 study, sponsored by Bausch Health Americas.

Terminated
Registry status
Phase 3
Development phase
1,881
Enrollment target

NCT01708629 is a Phase 3 study that was terminated before completion, run by Bausch Health Americas. The registered enrollment target is 1,881 participants.

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The verdict

NCT01708629, a Phase 3 study, was terminated before completion, sponsored by Bausch Health Americas.

TERMINATED
Registry status
Phase 3
Development phase
1,881 participants
Enrollment target

Study Summary

The purpose of this study is to assess the safety and efficacy of brodalumab at two different doses compared with placebo in participants with moderate to severe plaque psoriasis. A second purpose of this study is to assess the safety and efficacy brodalumab at two different doses compared with ustekinumab in participants with moderate to severe plaque psoriasis. A third purpose of this study is to assess the safety and efficacy of 4 maintenance regimens of brodalumab.

Interventions

  • DRUG placebo
  • DRUG ustekinumab
  • DRUG 210 mg brodalumab
  • DRUG 140 mg brodalumab

Trial Details

FieldValue
Enrollment Target 1,881 participants
Start Date 2012-09
Est. Completion 2015-10
Phase Phase 3

Sponsor

Bausch Health Americas

168 total trials

What the Registry Record Tells You About NCT01708629

The ClinicalTrials.gov registry entry for NCT01708629 describes a study currently listed as terminated, categorized as Phase 3. The registered enrollment target is 1,881 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Bausch Health Americas, which has 168 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which placebo is the first listed.

NCT01708629 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01708629 about?

NCT01708629 is a clinical study titled "Efficacy and Safety of Brodalumab Compared With Placebo and Ustekinumab in Moderate to Severe Plaque Psoriasis Subjects". The purpose of this study is to assess the safety and efficacy of brodalumab at two different doses compared with placebo in participants with moderate to severe plaque psoriasis. A second purpose of this study is to assess the safety and efficacy brodalumab at two different doses compared with ust...

What is the current status of trial NCT01708629?

This trial is currently terminated. It is a Phase 3 study. The enrollment target is 1,881 participants. The study started on 2012-09. Estimated completion is 2015-10.

What interventions are being tested in trial NCT01708629?

The interventions under investigation include: placebo (DRUG), ustekinumab (DRUG), 210 mg brodalumab (DRUG), 140 mg brodalumab (DRUG).

Who is sponsoring clinical trial NCT01708629?

This trial is sponsored by Bausch Health Americas, which has 168 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.