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NCT01704573 · ClinicalTrials.gov registry record
Nicotinic Receptor Levels After Stopping Smoking
A clinical trial, sponsored by University of Pennsylvania.
- Completed
- Registry status
- 20
- Enrollment target
NCT01704573: Completed study, sponsored by University of Pennsylvania.
NCT01704573 is a clinical trial that has completed, run by University of Pennsylvania. The registered enrollment target is 20 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01704573 has completed, sponsored by University of Pennsylvania.
- COMPLETED
- Registry status
- 20 participants
- Enrollment target
Study Summary
This positron emission tomography (PET) study examines the effects of 24 hours abstinence from smoking on return to availability of neuronal nicotinic receptors in slow and fast metabolizers of nicotine.
Primary Outcome
This study uses a mixed design. A within-subject positron emission tomography (PET) study comparing α4β2\* nAChR availability, using 2-\[18F\]FA PET imaging, at two timepoints (1) during smoking as usual; and (2) after 24 hours of overnight abstinence. The order of the PET scans will be counterbalanced across subjects to prevent order effects that could bias the study results. Nicotine metabolite ratio (NMR) serves as the between-subject factor. The minimum amount of time between scans will be
Interventions
- DRUG 2-[18F]-fluro-3-[2(S)-2-azethidinylmethoxy]-pyridine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2010-10 |
| Est. Completion | 2012-12 |
What the finished NCT01704573 record still lists
NCT01704573 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 20 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which 2-[18F]-fluro-3-[2(S)-2-azethidinylmethoxy]-pyridine is the first listed.
NCT01704573 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01704573 about?
NCT01704573 is a clinical study titled "Nicotinic Receptor Levels After Stopping Smoking". This positron emission tomography (PET) study examines the effects of 24 hours abstinence from smoking on return to availability of neuronal nicotinic receptors in slow and fast metabolizers of nicotine.
What is the current status of trial NCT01704573?
This trial is currently completed. The enrollment target is 20 participants. The study started on 2010-10. Estimated completion is 2012-12.
What interventions are being tested in trial NCT01704573?
The interventions under investigation include: 2-[18F]-fluro-3-[2(S)-2-azethidinylmethoxy]-pyridine (DRUG).
Who is sponsoring clinical trial NCT01704573?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
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