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NCT01702246 · ClinicalTrials.gov registry record · Phase 1
Effect of Simvastatin Treatment on Vaso-occlusive Pain in Sickle Cell Disease
A Phase 1 study, sponsored by UCSF Benioff Children's Hospital Oakland.
- Completed
- Registry status
- Phase 1
- Development phase
- 24
- Enrollment target
NCT01702246: Completed Phase 1 study, sponsored by UCSF Benioff Children's Hospital Oakland.
NCT01702246 is a Phase 1 study that has completed, run by UCSF Benioff Children's Hospital Oakland. The registered enrollment target is 24 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (60% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01702246, a Phase 1 study, has completed, sponsored by UCSF Benioff Children's Hospital Oakland.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 24 participants
- Enrollment target
Study Summary
The purpose of this study is to determine whether simvastatin is effective in reducing the frequency and intensity of vaso-occlusive pain episodes in patients with sickle cell disease.
Primary Outcome
The effect of simvastatin treatment will be assessed by measuring the difference from baseline in the mean frequency (and intensity) of vaso-occlusive pain events, after treatment with simvastatin. Pain rate (proportion of pain days) was defined as the number of days reported with sickle cell disease-related pain divided by the number of daily pain diaries completed.
Interventions
- DRUG Simvastatin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2012-02 |
| Est. Completion | 2015-06 |
| Phase | Phase 1 |
What the finished NCT01702246 record still lists
NCT01702246 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (60% lower).
The record links to 0 conditions, and to 1 intervention - of which Simvastatin is the first listed.
NCT01702246 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01702246 about?
NCT01702246 is a clinical study titled "Effect of Simvastatin Treatment on Vaso-occlusive Pain in Sickle Cell Disease". The purpose of this study is to determine whether simvastatin is effective in reducing the frequency and intensity of vaso-occlusive pain episodes in patients with sickle cell disease.
What is the current status of trial NCT01702246?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2012-02. Estimated completion is 2015-06.
What interventions are being tested in trial NCT01702246?
The interventions under investigation include: Simvastatin (DRUG).
Who is sponsoring clinical trial NCT01702246?
This trial is sponsored by UCSF Benioff Children's Hospital Oakland, which has 52 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01702246's enrollment target sits among peer trials
24 1520th of 2000 higher than 405 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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