Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT01698567 · ClinicalTrials.gov registry record · Phase 1

Antithrombin III in Infants With Cardiopulmonary Bypass (CPB)

A Phase 1 study, sponsored by University of Rochester.

Terminated
Registry status
Phase 1
Development phase
6
Enrollment target

NCT01698567: Clinical Trial Phase 1 study, sponsored by University of Rochester.

NCT01698567 is a Phase 1 study that was terminated before completion, run by University of Rochester. The registered enrollment target is 6 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT01698567, a Phase 1 study, was terminated before completion, sponsored by University of Rochester.

TERMINATED
Registry status
Phase 1
Development phase
6 participants
Enrollment target

Study Summary

The purpose of this study is to discern whether supplementation of Antithrombin III will decrease coagulation and inflammation associated with cardiopulmonary bypass in infants undergoing cardiac surgery.

Primary Outcome

Patients treated with ATIII as standard of care (good clinical practice) will remain in the study and be analyzed by their intention to treat group. Review of our clinical experience shows that treatment with ATIII for heparin resistance occurs in 2-3% of cases. If there are more than two patients so treated, we will also perform an "as-treated" analysis.

Interventions

  • DRUG Placebo
  • DRUG Antithrombin III

Trial Details

FieldValue
Enrollment Target 6 participants
Start Date 2012-07
Est. Completion 2016-03
Phase Phase 1
University of Rochester

636 total trials

Why NCT01698567 stopped before completion

NCT01698567 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (90% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT01698567 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01698567 about?

NCT01698567 is a clinical study titled "Antithrombin III in Infants With Cardiopulmonary Bypass (CPB)". The purpose of this study is to discern whether supplementation of Antithrombin III will decrease coagulation and inflammation associated with cardiopulmonary bypass in infants undergoing cardiac surgery.

What is the current status of trial NCT01698567?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 6 participants. The study started on 2012-07. Estimated completion is 2016-03.

What interventions are being tested in trial NCT01698567?

The interventions under investigation include: Placebo (DRUG), Antithrombin III (DRUG).

Who is sponsoring clinical trial NCT01698567?

This trial is sponsored by University of Rochester, which has 636 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01698567's enrollment target sits among peer trials

6 1974th of 2000 higher than 12 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT01698567, the US trial registry maintained by the National Library of Medicine. NCT01698567 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.