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NCT01694615 · ClinicalTrials.gov registry record · NA
Cryoprobe Transbronchial Lung Biopsy in Lung Transplant Patients
A NA study, sponsored by Johns Hopkins University.
- Completed
- Registry status
- NA
- Development phase
- 30
- Enrollment target
NCT01694615: Completed NA study, sponsored by Johns Hopkins University.
NCT01694615 is a NA study that has completed, run by Johns Hopkins University. The registered enrollment target is 30 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01694615, a NA study, has completed, sponsored by Johns Hopkins University.
- COMPLETED
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
Study Summary
Lung transplant recipients undergo bronchoscopy with biopsies for clinical indications and for surveillance in the diagnosis of acute rejection using standard transbronchial forceps. It is recognized that standard forceps biopsies underestimate the presence or degree of airway rejection due to crush artifact and sample size. Transbronchial cryobiopsies have been shown in the literature to provide larger samples without crush artifact in a safe fashion in lung cancer patients. The aim of this study is to determine if transbronchial cryobiopsy is superior to standard transbronchial forceps biopsies in regards to sample size, architecture and the diagnosis of early rejection in lung transplant recipients which if discovered earlier may improve survival.
Primary Outcome
Direct measurements of pathologic specimens from the forceps and cryoprobe will be compared. In addition, amount of crush artifact will alse be directly measured and compared utilizing pathology software which measures area of viable tissue.
Interventions
- PROCEDURE Cryoprobe biopsy
- PROCEDURE Forceps Biopsy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2011-11 |
| Est. Completion | 2015-09 |
| Phase | NA |
What the finished NCT01694615 record still lists
NCT01694615 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which Cryoprobe biopsy is the first listed.
NCT01694615 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01694615 about?
NCT01694615 is a clinical study titled "Cryoprobe Transbronchial Lung Biopsy in Lung Transplant Patients". Lung transplant recipients undergo bronchoscopy with biopsies for clinical indications and for surveillance in the diagnosis of acute rejection using standard transbronchial forceps. It is recognized that standard forceps biopsies underestimate the presence or degree of airway rejection due to crush...
What is the current status of trial NCT01694615?
This trial is currently completed. It is a NA study. The enrollment target is 30 participants. The study started on 2011-11. Estimated completion is 2015-09.
What interventions are being tested in trial NCT01694615?
The interventions under investigation include: Cryoprobe biopsy (PROCEDURE), Forceps Biopsy (PROCEDURE).
Who is sponsoring clinical trial NCT01694615?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01694615's enrollment target sits among peer trials
30 1593rd of 2000 higher than 299 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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