Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT01694277 · ClinicalTrials.gov registry record · Phase 3
Masitinib in Patients With Gastrointestinal Stromal Tumour After Progression With Imatinib
A Phase 3 study, sponsored by AB Science.
- Completed
- Registry status
- Phase 3
- Development phase
- 258
- Enrollment target
NCT01694277: Completed Phase 3 study, sponsored by AB Science.
NCT01694277 is a Phase 3 study that has completed, run by AB Science. The registered enrollment target is 258 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (67% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01694277, a Phase 3 study, has completed, sponsored by AB Science.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 258 participants
- Enrollment target
Study Summary
The objective is to compare the efficacy and safety of masitinib at 12 mg/kg/day to sunitinib at 50 mg/day in the treatment of patients with gastro-intestinal stromal tumor (GIST) after progression with imatinib.
Primary Outcome
Overall survival is defined as time in months from the randomization date to the date of death due to any cause. If a patient is not known to have died, then OS will be censored at the date of last known date patient alive.
Interventions
- DRUG Sunitinib
- DRUG Masitinib
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 258 participants |
| Start Date | 2012-04 |
| Est. Completion | 2020-12 |
| Phase | Phase 3 |
What the finished NCT01694277 record still lists
NCT01694277 is an interventional study that assigns participants to a tested intervention. The registered 258 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (67% lower).
The record links to 0 conditions, and to 2 interventions - of which Sunitinib is the first listed.
NCT01694277 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01694277 about?
NCT01694277 is a clinical study titled "Masitinib in Patients With Gastrointestinal Stromal Tumour After Progression With Imatinib". The objective is to compare the efficacy and safety of masitinib at 12 mg/kg/day to sunitinib at 50 mg/day in the treatment of patients with gastro-intestinal stromal tumor (GIST) after progression with imatinib.
What is the current status of trial NCT01694277?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 258 participants. The study started on 2012-04. Estimated completion is 2020-12.
What interventions are being tested in trial NCT01694277?
The interventions under investigation include: Sunitinib (DRUG), Masitinib (DRUG).
Who is sponsoring clinical trial NCT01694277?
This trial is sponsored by AB Science, which has 8 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01694277's enrollment target sits among peer trials
258 1235th of 2000 higher than 763 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT03785288 · 258 participants · Phase 3
Vaginal Cuff Brachytherapy Fractionation Study
- NCT04643002 · 258 participants · Phase 1
Isatuximab in Combination With Novel Agents in RRMM - Master Protocol
- NCT04924322 · 258 participants · Phase 2
Catheter-Related Early Thromboprophylaxis With Enoxaparin Studies
- NCT05043012 · 258 participants · NA
Diagnostic Performance Of Non-Endorectal Coil Multiparametric Magnetic Resonance Imaging Of Prostate With Flexible AIR Coil (DoNEMAC Study)
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia