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NCT01682499 · ClinicalTrials.gov registry record · Phase 1
Calcium and Magnesium Infusion for the Prevention of Taxane Induced Neuropathy
A Phase 1 study, sponsored by Beth Israel Medical Center.
- Completed
- Registry status
- Phase 1
- Development phase
- 50
- Enrollment target
NCT01682499: Completed Phase 1 study, sponsored by Beth Israel Medical Center.
NCT01682499 is a Phase 1 study that has completed, run by Beth Israel Medical Center. The registered enrollment target is 50 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (17% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01682499, a Phase 1 study, has completed, sponsored by Beth Israel Medical Center.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 50 participants
- Enrollment target
Study Summary
This is a pilot study evaluating the feasibility of intravenous calcium and magnesium (Ca/Mg) infusion for prevention of taxane induced neuropathy in patients with early stage breast cancer receiving adjuvant or neo-adjuvant paclitaxel, either given every 2 weeks for 4 cycles or every week for 12 weeks.
Primary Outcome
The primary aim of this study is to assess paclitaxel-related neuropathy (grade 2 or greater) as measured by NCI Common Terminology Criteria Version 3 in patients receiving Ca/Mg infusion during paclitaxel chemotherapy and compare it with historical controls
Interventions
- DRUG calcium gluconate and magnesium sulfate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2012-08 |
| Est. Completion | 2014-08 |
| Phase | Phase 1 |
What the finished NCT01682499 record still lists
NCT01682499 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (17% lower).
The record links to 0 conditions, and to 1 intervention - of which calcium gluconate and magnesium sulfate is the first listed.
NCT01682499 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01682499 about?
NCT01682499 is a clinical study titled "Calcium and Magnesium Infusion for the Prevention of Taxane Induced Neuropathy". This is a pilot study evaluating the feasibility of intravenous calcium and magnesium (Ca/Mg) infusion for prevention of taxane induced neuropathy in patients with early stage breast cancer receiving adjuvant or neo-adjuvant paclitaxel, either given every 2 weeks for 4 cycles or every week for 12 we...
What is the current status of trial NCT01682499?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 50 participants. The study started on 2012-08. Estimated completion is 2014-08.
What interventions are being tested in trial NCT01682499?
The interventions under investigation include: calcium gluconate and magnesium sulfate (DRUG).
Who is sponsoring clinical trial NCT01682499?
This trial is sponsored by Beth Israel Medical Center, which has 44 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01682499's enrollment target sits among peer trials
50 973rd of 2000 higher than 984 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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