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NCT01681576 · ClinicalTrials.gov registry record · Phase 2

Assessment of LCZ696 and Valsartan in Asian Patients With Salt-sensitive Hypertension

A Phase 2 study, sponsored by Novartis Pharmaceuticals.

Completed
Registry status
Phase 2
Development phase
72
Enrollment target

NCT01681576: Completed Phase 2 study, sponsored by Novartis Pharmaceuticals.

NCT01681576 is a Phase 2 study that has completed, run by Novartis Pharmaceuticals. The registered enrollment target is 72 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (46% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01681576, a Phase 2 study, has completed, sponsored by Novartis Pharmaceuticals.

COMPLETED
Registry status
Phase 2
Development phase
72 participants
Enrollment target

Study Summary

This study will evaluate the effect of LCZ696 and valsartan on natriuresis, diuresis, and blood pressure in salt-sensitive Asian hypertensive patients.

Primary Outcome

Urine will be collected in fractions of 6 to 24 hours post-dose. From each fraction, a sample will be drawn for analysis of sodium Day 1

Interventions

  • DRUG Valsartan
  • DRUG LCZ696

Trial Details

FieldValue
Enrollment Target 72 participants
Start Date 2012-08
Est. Completion 2013-10
Phase Phase 2
Novartis Pharmaceuticals

1,375 total trials

What the finished NCT01681576 record still lists

NCT01681576 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 72 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (46% lower).

The record links to 0 conditions, and to 2 interventions - of which Valsartan is the first listed.

NCT01681576 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01681576 about?

NCT01681576 is a clinical study titled "Assessment of LCZ696 and Valsartan in Asian Patients With Salt-sensitive Hypertension". This study will evaluate the effect of LCZ696 and valsartan on natriuresis, diuresis, and blood pressure in salt-sensitive Asian hypertensive patients.

What is the current status of trial NCT01681576?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 72 participants. The study started on 2012-08. Estimated completion is 2013-10.

What interventions are being tested in trial NCT01681576?

The interventions under investigation include: Valsartan (DRUG), LCZ696 (DRUG).

Who is sponsoring clinical trial NCT01681576?

This trial is sponsored by Novartis Pharmaceuticals, which has 1,375 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01681576's enrollment target sits among peer trials

72 925th of 2000 higher than 1,065 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01681576, the US trial registry maintained by the National Library of Medicine. NCT01681576 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.