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NCT01672814 · ClinicalTrials.gov registry record · Phase 3
Microwave Treatment and Corneal Collagen Crosslinking for Keratoconus
A Phase 3 study, sponsored by Cornea and Laser Eye Institute.
- Completed
- Registry status
- Phase 3
- Development phase
- 3
- Enrollment target
NCT01672814: Completed Phase 3 study, sponsored by Cornea and Laser Eye Institute.
NCT01672814 is a Phase 3 study that has completed, run by Cornea and Laser Eye Institute. The registered enrollment target is 3 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01672814, a Phase 3 study, has completed, sponsored by Cornea and Laser Eye Institute.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 3 participants
- Enrollment target
Study Summary
This study compares the outcomes of the Vedera KXS procedure (a microwave-based procedure, also known as Keraflex) combined with corneal collagen crosslinking to corneal collagen crosslinking alone for the treatment of keratoconus. The goal is to improve corneal shape in patients with keratoconus.
Primary Outcome
The change in maximum keratometry (Kmax) from baseline will be evaluated at 12 months for all eyes randomized to the two treatment groups. As a secondary analysis of this endpoint,the change in maximum keratometry (Kmax)from baseline will be evaluated at 1,3 and 6 months for all eyes.
Interventions
- DRUG riboflavin ophthalmic solution
- DEVICE Vedera KXS Microwave System
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3 participants |
| Start Date | 2012-08 |
| Est. Completion | 2017-06-01 |
| Phase | Phase 3 |
What the finished NCT01672814 record still lists
NCT01672814 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 3 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 2 interventions - of which riboflavin ophthalmic solution is the first listed.
NCT01672814 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01672814 about?
NCT01672814 is a clinical study titled "Microwave Treatment and Corneal Collagen Crosslinking for Keratoconus". This study compares the outcomes of the Vedera KXS procedure (a microwave-based procedure, also known as Keraflex) combined with corneal collagen crosslinking to corneal collagen crosslinking alone for the treatment of keratoconus. The goal is to improve corneal shape in patients with keratoconus.
What is the current status of trial NCT01672814?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 3 participants. The study started on 2012-08. Estimated completion is 2017-06-01.
What interventions are being tested in trial NCT01672814?
The interventions under investigation include: riboflavin ophthalmic solution (DRUG), Vedera KXS Microwave System (DEVICE).
Who is sponsoring clinical trial NCT01672814?
This trial is sponsored by Cornea and Laser Eye Institute, which has 2 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01672814's enrollment target sits among peer trials
3 1999th of 2000 higher than 1 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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