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NCT01667783 · ClinicalTrials.gov registry record · Phase 2

Improving Diabetes Through Lifestyle and Surgery

A Phase 2 study, sponsored by Johns Hopkins University.

Completed
Registry status
Phase 2
Development phase
15
Enrollment target

NCT01667783: Completed Phase 2 study, sponsored by Johns Hopkins University.

NCT01667783 is a Phase 2 study that has completed, run by Johns Hopkins University. The registered enrollment target is 15 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (89% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT01667783, a Phase 2 study, has completed, sponsored by Johns Hopkins University.

COMPLETED
Registry status
Phase 2
Development phase
15 participants
Enrollment target

Study Summary

Weight loss is effective in reducing many complications of obesity, with the majority of patients who undergo bariatric surgery having substantial improvements in their weight-related illnesses. The investigators propose a pilot study in 45 subjects with mild to moderate obesity to compare how losing 10% of initial body weight via one of three common weight loss strategies (medical weight loss with a low calorie diet, Roux-en-Y gastric bypass surgery, and adjustable gastric banding) affects diabetes. While the investigators do not expect this pilot study to provide definitive answers, it will provide valuable information to design a larger trial which will help guide therapy for people with mild-moderate obesity and substantial comorbidities.

Primary Outcome

Participants will be followed until they reach 10% weight loss, anticipated average time 6 months, or up to 9 months.

Interventions

  • PROCEDURE Gastric Bypass
  • PROCEDURE Gastric Banding
  • BEHAVIORAL Medical Weight Loss

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2012-08
Est. Completion 2015-02
Phase Phase 2
Johns Hopkins University

1,448 total trials

What the finished NCT01667783 record still lists

NCT01667783 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (89% lower).

The record links to 0 conditions, and to 3 interventions - of which Gastric Bypass is the first listed.

NCT01667783 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01667783 about?

NCT01667783 is a clinical study titled "Improving Diabetes Through Lifestyle and Surgery". Weight loss is effective in reducing many complications of obesity, with the majority of patients who undergo bariatric surgery having substantial improvements in their weight-related illnesses. The investigators propose a pilot study in 45 subjects with mild to moderate obesity to compare how losin...

What is the current status of trial NCT01667783?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 15 participants. The study started on 2012-08. Estimated completion is 2015-02.

What interventions are being tested in trial NCT01667783?

The interventions under investigation include: Gastric Bypass (PROCEDURE), Gastric Banding (PROCEDURE), Medical Weight Loss (BEHAVIORAL).

Who is sponsoring clinical trial NCT01667783?

This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01667783's enrollment target sits among peer trials

15 1919th of 2000 higher than 60 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01667783, the US trial registry maintained by the National Library of Medicine. NCT01667783 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.