Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT01660009 · ClinicalTrials.gov registry record · NA
Adverse Effects of Systemic Hypoglycemia Exposure on Endothelial Function in Humans
A NA study, sponsored by Medical College of Wisconsin.
- Terminated
- Registry status
- NA
- Development phase
- 5
- Enrollment target
NCT01660009: Clinical Trial NA study, sponsored by Medical College of Wisconsin.
NCT01660009 is a NA study that was terminated before completion, run by Medical College of Wisconsin. The registered enrollment target is 5 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01660009, a NA study, was terminated before completion, sponsored by Medical College of Wisconsin.
- TERMINATED
- Registry status
- NA
- Development phase
- 5 participants
- Enrollment target
Study Summary
Prior work suggests exposure to low glucose levels (hypoglycemia) is associated with increased cardiovascular risk. However, whether there is a causal relationship between cardiovascular events and hypoglycemia remains unclear with conflicting data in the literature. In this study, we plan to study whether acute exposure of patients to clinically relevant (50-60 milligrams/deciliter) levels of hypoglycemia induces or worsens blood vessel endothelial dysfunction- a key 1st step in the development of heart attacks and strokes. This will be determined in humans both with and with type 2 diabetes.
Interventions
- OTHER Glycemic clamping
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5 participants |
| Start Date | 2012-06 |
| Est. Completion | 2017-06 |
| Phase | NA |
Why NCT01660009 stopped before completion
NCT01660009 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 5 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 1 intervention - of which Glycemic clamping is the first listed.
NCT01660009 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01660009 about?
NCT01660009 is a clinical study titled "Adverse Effects of Systemic Hypoglycemia Exposure on Endothelial Function in Humans". Prior work suggests exposure to low glucose levels (hypoglycemia) is associated with increased cardiovascular risk. However, whether there is a causal relationship between cardiovascular events and hypoglycemia remains unclear with conflicting data in the literature. In this study, we plan to study ...
What is the current status of trial NCT01660009?
This trial is currently terminated. It is a NA study. The enrollment target is 5 participants. The study started on 2012-06. Estimated completion is 2017-06.
What interventions are being tested in trial NCT01660009?
The interventions under investigation include: Glycemic clamping (OTHER).
Who is sponsoring clinical trial NCT01660009?
This trial is sponsored by Medical College of Wisconsin, which has 447 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01660009's enrollment target sits among peer trials
5 1988th of 2000 higher than 5 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia