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NCT01657903 · ClinicalTrials.gov registry record · NA
Evaluation of Efficacy of Experimental Gel to Foam Dentifrices in Dental Erosion
A NA study, sponsored by GlaxoSmithKline.
- Completed
- Registry status
- NA
- Development phase
- 56
- Enrollment target
NCT01657903: Completed NA study, sponsored by GlaxoSmithKline.
NCT01657903 is a NA study that has completed, run by GlaxoSmithKline. The registered enrollment target is 56 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01657903, a NA study, has completed, sponsored by GlaxoSmithKline.
- COMPLETED
- Registry status
- NA
- Development phase
- 56 participants
- Enrollment target
Study Summary
The purpose of this study is to compare and evaluate the ability of two European Union (EU) regulated gel to foam toothpaste formulations versus a non-fluoride toothpaste using a modified in-situ model of dental erosion and remineralization. A positive control i.e fluoride containing toothpaste marketed in EU will also be compared to non-fluoride toothpaste.
Primary Outcome
Enamel specimens were exposed to dietary erosive challenge and set of five indentations within each specimen was measured. Decrease in the indentation length compared to the baseline indicates hardening of enamel surface. Enamel specimens were exposed to second erosion challenge to determine RER which compared the indentations values of enamel specimens at baseline (B), first erosive (E1) and second erosive challenge (E2). Percent RER was calculated by formula: \[(E1-E2)/ (E1-B)\]\*100. Smaller
Interventions
- DRUG Sodium Fluoride
- DRUG Potassium nitrate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 56 participants |
| Start Date | 2011-11 |
| Est. Completion | 2012-02 |
| Phase | NA |
What the finished NCT01657903 record still lists
NCT01657903 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 56 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 2 interventions - of which Sodium Fluoride is the first listed.
NCT01657903 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01657903 about?
NCT01657903 is a clinical study titled "Evaluation of Efficacy of Experimental Gel to Foam Dentifrices in Dental Erosion". The purpose of this study is to compare and evaluate the ability of two European Union (EU) regulated gel to foam toothpaste formulations versus a non-fluoride toothpaste using a modified in-situ model of dental erosion and remineralization. A positive control i.e fluoride containing toothpaste mark...
What is the current status of trial NCT01657903?
This trial is currently completed. It is a NA study. The enrollment target is 56 participants. The study started on 2011-11. Estimated completion is 2012-02.
What interventions are being tested in trial NCT01657903?
The interventions under investigation include: Sodium Fluoride (DRUG), Potassium nitrate (DRUG).
Who is sponsoring clinical trial NCT01657903?
This trial is sponsored by GlaxoSmithKline, which has 1,345 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01657903's enrollment target sits among peer trials
56 1262nd of 2000 higher than 737 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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