Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT01652534 · ClinicalTrials.gov registry record · Phase 3
Efficacy Study of Amantadine to Treat Gait Dysfunction and Freezing in Parkinson's Disease
A Phase 3 study, sponsored by Northwestern University.
- Terminated
- Registry status
- Phase 3
- Development phase
- 3
- Enrollment target
NCT01652534: Clinical Trial Phase 3 study, sponsored by Northwestern University.
NCT01652534 is a Phase 3 study that was terminated before completion, run by Northwestern University. The registered enrollment target is 3 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01652534, a Phase 3 study, was terminated before completion, sponsored by Northwestern University.
- TERMINATED
- Registry status
- Phase 3
- Development phase
- 3 participants
- Enrollment target
Study Summary
The purpose of this study is to explore the efficacy of the drug Amantadine for the treatment of freezing of gait in patients with Parkinson's Disease. The investigators hypothesize that amantadine is useful for management of freezing of gait in subjects with Parkinson's Disease.
Primary Outcome
This is a walking assessment. The subject will begin in the seated position, stand up, walk 7 meters, turn around, and sit back down. The entire process from leaving the chair to returning to the chair will be timed. Also, the Timed Up and Go (TUG) will be done both in the ON and OFF states.
Interventions
- DRUG Placebo
- DRUG Amantadine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3 participants |
| Start Date | 2011-06 |
| Est. Completion | 2015-08 |
| Phase | Phase 3 |
Why NCT01652534 stopped before completion
NCT01652534 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 3 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT01652534 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01652534 about?
NCT01652534 is a clinical study titled "Efficacy Study of Amantadine to Treat Gait Dysfunction and Freezing in Parkinson's Disease". The purpose of this study is to explore the efficacy of the drug Amantadine for the treatment of freezing of gait in patients with Parkinson's Disease. The investigators hypothesize that amantadine is useful for management of freezing of gait in subjects with Parkinson's Disease.
What is the current status of trial NCT01652534?
This trial is currently terminated. It is a Phase 3 study. The enrollment target is 3 participants. The study started on 2011-06. Estimated completion is 2015-08.
What interventions are being tested in trial NCT01652534?
The interventions under investigation include: Placebo (DRUG), Amantadine (DRUG).
Who is sponsoring clinical trial NCT01652534?
This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01652534's enrollment target sits among peer trials
3 1999th of 2000 higher than 1 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia