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NCT01636817 · ClinicalTrials.gov registry record · Phase 2

A Trial of NNC0109-0012, an Anti-IL-20 Biologic, in Patients With Active Rheumatoid Arthritis Who Are Inadequate Responders to Anti-TNFa Biologics

A Phase 2 study, sponsored by Novo Nordisk A/S.

Terminated
Registry status
Phase 2
Development phase
239
Enrollment target

NCT01636817: Clinical Trial Phase 2 study, sponsored by Novo Nordisk A/S.

NCT01636817 is a Phase 2 study that was terminated before completion, run by Novo Nordisk A/S. The registered enrollment target is 239 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (80% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01636817, a Phase 2 study, was terminated before completion, sponsored by Novo Nordisk A/S.

TERMINATED
Registry status
Phase 2
Development phase
239 participants
Enrollment target

Study Summary

This trial is conducted in Europe, North America and South America. The aim of this trial is to investigate the clinical efficacy of NNC0109-0012, a human monoclonal antibody, compared to placebo when administered as weekly s.c. (subcutaneous, under the skin) injections to patients with active rheumatoid arthritis (RA) who are inadequate responders to anti-TNFa biologics and are on a stable background of methotrexate (MTX) therapy.

Interventions

  • DRUG placebo
  • DRUG NNC0109-0012

Trial Details

FieldValue
Enrollment Target 239 participants
Start Date 2012-08
Est. Completion 2014-11
Phase Phase 2
Novo Nordisk A/S

431 total trials

Why NCT01636817 stopped before completion

NCT01636817 is an interventional study that assigns participants to a tested intervention. The registered 239 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (80% higher).

The record links to 0 conditions, and to 2 interventions - of which placebo is the first listed.

NCT01636817 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01636817 about?

NCT01636817 is a clinical study titled "A Trial of NNC0109-0012, an Anti-IL-20 Biologic, in Patients With Active Rheumatoid Arthritis Who Are Inadequate Responders to Anti-TNFa Biologics". This trial is conducted in Europe, North America and South America. The aim of this trial is to investigate the clinical efficacy of NNC0109-0012, a human monoclonal antibody, compared to placebo when administered as weekly s.c. (subcutaneous, under the skin) injections to patients with active rheum...

What is the current status of trial NCT01636817?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 239 participants. The study started on 2012-08. Estimated completion is 2014-11.

What interventions are being tested in trial NCT01636817?

The interventions under investigation include: placebo (DRUG), NNC0109-0012 (DRUG).

Who is sponsoring clinical trial NCT01636817?

This trial is sponsored by Novo Nordisk A/S, which has 431 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01636817's enrollment target sits among peer trials

239 255th of 2000 higher than 1,746 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01636817, the US trial registry maintained by the National Library of Medicine. NCT01636817 (mid enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.