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NCT01621646 · ClinicalTrials.gov registry record · NA
The Effect of Daily Consumption of Eggs on Cognitive Function in the Elderly
A NA study, sponsored by Tufts University.
- Completed
- Registry status
- NA
- Development phase
- 44
- Enrollment target
NCT01621646: Completed NA study, sponsored by Tufts University.
NCT01621646 is a NA study that has completed, run by Tufts University. The registered enrollment target is 44 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01621646, a NA study, has completed, sponsored by Tufts University.
- COMPLETED
- Registry status
- NA
- Development phase
- 44 participants
- Enrollment target
Study Summary
Cognitive impairment is also a major risk factor for development of dementia later in life. Findings from our studies suggest that the carotenoids, lutein and zeaxanthin may be important in cognitive function in the elderly. The investigators have previously reported eggs to be a highly bioavailable source of lutein and zeaxanthin. Our study evaluates long-term egg intervention as a treatment strategy for age-related cognitive impairment which could possibly prevent the onset of dementia. The investigators have also shown that lutein supplementation significantly improved verbal fluency scores in healthy older women. Our studies have shown that egg interventions can significantly increase serum lutein concentrations in older adults. Based on the sum of our findings, the next logical step will be to investigate the ability of lutein and zeaxanthin contained in eggs to influence cognitive function in older adults. The investigators hypothesize that there will be a significant increase in cognitive function measures in older adults provided with meals containing 2 egg/day at the end of 6 months, while no significant improvements will be observed in older adults given daily meals containing egg substitute. The proposed study is designed as a randomized, placebo controlled trial that tests the effects of 6 month supplementation with 2 eggs/day on cognitive function in older adults. Secondary analyses will determine whether baseline MP density predicts relative effectiveness of the intervention on cognitive function. Secondary outcomes include plasma biomarkers of oxidative stress and inflammation.
Primary Outcome
measures of attention, executive function, verbal fluency will be made using a sensitive computerized program
Interventions
- OTHER eggs or egg whites
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 44 participants |
| Start Date | 2012-07 |
| Est. Completion | 2015-08 |
| Phase | NA |
What the finished NCT01621646 record still lists
NCT01621646 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 44 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 1 intervention - of which eggs or egg whites is the first listed.
NCT01621646 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01621646 about?
NCT01621646 is a clinical study titled "The Effect of Daily Consumption of Eggs on Cognitive Function in the Elderly". Cognitive impairment is also a major risk factor for development of dementia later in life. Findings from our studies suggest that the carotenoids, lutein and zeaxanthin may be important in cognitive function in the elderly. The investigators have previously reported eggs to be a highly bioavailable...
What is the current status of trial NCT01621646?
This trial is currently completed. It is a NA study. The enrollment target is 44 participants. The study started on 2012-07. Estimated completion is 2015-08.
What interventions are being tested in trial NCT01621646?
The interventions under investigation include: eggs or egg whites (OTHER).
Who is sponsoring clinical trial NCT01621646?
This trial is sponsored by Tufts University, which has 163 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01621646's enrollment target sits among peer trials
44 1423rd of 2000 higher than 566 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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