Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT01607268 · ClinicalTrials.gov registry record
Magnetic Resonance Spectroscopy in Autonomic Failure
A clinical trial, sponsored by Vanderbilt University.
- Terminated
- Registry status
- 6
- Enrollment target
NCT01607268 is a clinical trial that was terminated before completion, run by Vanderbilt University. The registered enrollment target is 6 participants.
The verdict
NCT01607268 was terminated before completion, sponsored by Vanderbilt University.
- TERMINATED
- Registry status
- 6 participants
- Enrollment target
Study Summary
This research study will be conducted in patients with primary autonomic failure, a disabling condition that is associated with low blood pressure upon standing. These patients are also not able to control for changes in their blood pressure due to a loss of cardiovascular reflexes that are mediated within the brain. The purpose of this study is to determine whether magnetic resonance spectroscopy (MRS), a non-invasive imaging technique, can measure levels of chemicals (neurotransmitters) in the dorsal medulla, a brain area important for control of cardiovascular function, in autonomic failure patients. Importantly, this study will determine whether there are differences in brain chemicals between patients with peripheral versus central origins of their autonomic failure. The hypothesis is that the neurotransmitter profile in the medulla will be intact in patients with peripheral autonomic failure compared to those with central impairment. Overall, this study will provide insight into understanding the mechanisms involved in autonomic failure and will determine whether a single session of MRS imaging can improve the ability to make an accurate diagnosis in these patients. This would lessen the need for more extensive and invasive clinical testing.
Interventions
- PROCEDURE Magnetic Resonance Spectroscopy Imaging
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 6 participants |
| Start Date | 2012-07 |
| Est. Completion | 2017-01 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01607268
The ClinicalTrials.gov registry entry for NCT01607268 describes a study currently listed as terminated, categorized as an unspecified phase. The registered enrollment target is 6 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Vanderbilt University, which has 430 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Magnetic Resonance Spectroscopy Imaging is the first listed.
NCT01607268 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01607268 about?
NCT01607268 is a clinical study titled "Magnetic Resonance Spectroscopy in Autonomic Failure". This research study will be conducted in patients with primary autonomic failure, a disabling condition that is associated with low blood pressure upon standing. These patients are also not able to control for changes in their blood pressure due to a loss of cardiovascular reflexes that are mediated...
What is the current status of trial NCT01607268?
This trial is currently terminated. The enrollment target is 6 participants. The study started on 2012-07. Estimated completion is 2017-01.
What interventions are being tested in trial NCT01607268?
The interventions under investigation include: Magnetic Resonance Spectroscopy Imaging (PROCEDURE).
Who is sponsoring clinical trial NCT01607268?
This trial is sponsored by Vanderbilt University, which has 430 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.