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NCT01605435 · ClinicalTrials.gov registry record · Phase 2
Ghrelin Dose Finding In Frail Elderly
A Phase 2 study, sponsored by University of Pennsylvania.
- Completed
- Registry status
- Phase 2
- Development phase
- 5
- Enrollment target
NCT01605435: Completed Phase 2 study, sponsored by University of Pennsylvania.
NCT01605435 is a Phase 2 study that has completed, run by University of Pennsylvania. The registered enrollment target is 5 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01605435, a Phase 2 study, has completed, sponsored by University of Pennsylvania.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 5 participants
- Enrollment target
Study Summary
Frailty is a geriatric syndrome leading to physical deterioration including muscle wasting (sarcopenia) and unintentional weight loss. There are currently no approved therapies for frailty. Ghrelin is a hormone produced by the stomach that stimulates appetite centers in the brain. The purpose of this study is to determine the optimal subcutaneous ghrelin dose as a potential intervention for frail elderly individuals. We will examine food intake and metabolic parameters after placebo and ghrelin administration at three escalating subcutaneously administered doses.
Primary Outcome
Number and type of treatment emergent adverse events
Interventions
- DRUG Ghrelin Group 1
- DRUG Ghrelin Group 2
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5 participants |
| Start Date | 2012-05 |
| Est. Completion | 2012-12 |
| Phase | Phase 2 |
What the finished NCT01605435 record still lists
NCT01605435 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 5 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 2 interventions - of which Ghrelin Group 1 is the first listed.
NCT01605435 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01605435 about?
NCT01605435 is a clinical study titled "Ghrelin Dose Finding In Frail Elderly". Frailty is a geriatric syndrome leading to physical deterioration including muscle wasting (sarcopenia) and unintentional weight loss. There are currently no approved therapies for frailty. Ghrelin is a hormone produced by the stomach that stimulates appetite centers in the brain. The purpose of thi...
What is the current status of trial NCT01605435?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 5 participants. The study started on 2012-05. Estimated completion is 2012-12.
What interventions are being tested in trial NCT01605435?
The interventions under investigation include: Ghrelin Group 1 (DRUG), Ghrelin Group 2 (DRUG).
Who is sponsoring clinical trial NCT01605435?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01605435's enrollment target sits among peer trials
5 2000th of 2000 the lowest of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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