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NCT01599260 · ClinicalTrials.gov registry record · NA

Resistance Exercise in Rheumatic Disease

A NA study, sponsored by Johns Hopkins University.

Terminated
Registry status
NA
Development phase
15
Enrollment target

NCT01599260: Clinical Trial NA study, sponsored by Johns Hopkins University.

NCT01599260 is a NA study that was terminated before completion, run by Johns Hopkins University. The registered enrollment target is 15 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01599260, a NA study, was terminated before completion, sponsored by Johns Hopkins University.

TERMINATED
Registry status
NA
Development phase
15 participants
Enrollment target

Study Summary

People with rheumatic disease often have decreased strength, muscle mass, and bone mineral density due to repeated bouts of inflammation, normal effects of aging, disuse, and inactivity. The medications used to quell the disease process, such as prednisone, can also have detrimental effects on body composition, strength, and functional capacity. The investigators propose to investigate the feasibility, safety, and effects of resistance exercise in older patients with rheumatoid arthritis (RA) and vasculitis. The unique resistance protocol the investigators propose involves performing movements in a slow and controlled fashion (i.e., no acceleration or use of momentum in the lifting and lowering of the resistance) to minimize force on the joints and connective tissues. This will be conducted in an individually-supervised environment with a new generation of exercise equipment that will accommodate their musculoskeletal capabilities and allow for reproducibility of the exercise protocol. The investigators intend to investigate the feasibility, safety, musculoskeletal, and psychological effects of this resistance exercise protocol in older patients with rheumatoid arthritis and vasculitis by testing their strength, body composition, functional ability, mood, and quality of life before and after this 16-week resistance exercise intervention.

Primary Outcome

Participants will be provided with questionnaires. They will be asked to report the number of arthritis flares since the last visit. Arthritis flares consist of pain and swelling of the joints. The total number of flares during the 16 week study will be reported.

Interventions

  • OTHER Resistance Exercise

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2012-05
Est. Completion 2018-12
Phase NA
Johns Hopkins University

1,448 total trials

Why NCT01599260 stopped before completion

NCT01599260 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 1 intervention - of which Resistance Exercise is the first listed.

NCT01599260 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01599260 about?

NCT01599260 is a clinical study titled "Resistance Exercise in Rheumatic Disease". People with rheumatic disease often have decreased strength, muscle mass, and bone mineral density due to repeated bouts of inflammation, normal effects of aging, disuse, and inactivity. The medications used to quell the disease process, such as prednisone, can also have detrimental effects on body ...

What is the current status of trial NCT01599260?

This trial is currently terminated. It is a NA study. The enrollment target is 15 participants. The study started on 2012-05. Estimated completion is 2018-12.

What interventions are being tested in trial NCT01599260?

The interventions under investigation include: Resistance Exercise (OTHER).

Who is sponsoring clinical trial NCT01599260?

This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01599260's enrollment target sits among peer trials

15 1881st of 2000 higher than 92 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01599260, the US trial registry maintained by the National Library of Medicine. NCT01599260 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.