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NCT01595386 · ClinicalTrials.gov registry record · NA

Effect of Postop Steroids on Cardiovascular/Respiratory Function in Neonates Undergoing Cardiopulmonary Bypass

A NA study, sponsored by University of Alabama at Birmingham.

Completed
Registry status
NA
Development phase
40
Enrollment target

NCT01595386: Completed NA study, sponsored by University of Alabama at Birmingham.

NCT01595386 is a NA study that has completed, run by University of Alabama at Birmingham. The registered enrollment target is 40 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01595386, a NA study, has completed, sponsored by University of Alabama at Birmingham.

COMPLETED
Registry status
NA
Development phase
40 participants
Enrollment target

Study Summary

This protocol is designed to offer insight into critical illness related corticosteroid insufficiency and steroid supplementation in neonates undergoing cardiac surgery with cardiopulmonary bypass by administering exogenous steroids in the immediate post-operative period.

Primary Outcome

Low Cardiac Output Syndrome (LCOS) within the first 48 hours after post-operative admission to the Pediatric Cardiac Intensive Care Unit was used as the primary outcome. This was defined as a double in inotropic support from post-operative admit, requiring Extracorporeal Membrane Oxygenation (ECMO) support, receiving Cardiopulmonary Resuscitation, or death.

Interventions

  • DRUG Hydrocortisone
  • DRUG Normal Saline

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2012-04
Est. Completion 2013-11
Phase NA
University of Alabama at Birmingham

1,160 total trials

What the finished NCT01595386 record still lists

NCT01595386 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).

The record links to 0 conditions, and to 2 interventions - of which Hydrocortisone is the first listed.

NCT01595386 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01595386 about?

NCT01595386 is a clinical study titled "Effect of Postop Steroids on Cardiovascular/Respiratory Function in Neonates Undergoing Cardiopulmonary Bypass". This protocol is designed to offer insight into critical illness related corticosteroid insufficiency and steroid supplementation in neonates undergoing cardiac surgery with cardiopulmonary bypass by administering exogenous steroids in the immediate post-operative period.

What is the current status of trial NCT01595386?

This trial is currently completed. It is a NA study. The enrollment target is 40 participants. The study started on 2012-04. Estimated completion is 2013-11.

What interventions are being tested in trial NCT01595386?

The interventions under investigation include: Hydrocortisone (DRUG), Normal Saline (DRUG).

Who is sponsoring clinical trial NCT01595386?

This trial is sponsored by University of Alabama at Birmingham, which has 1,160 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01595386's enrollment target sits among peer trials

40 1447th of 2000 higher than 465 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01595386, the US trial registry maintained by the National Library of Medicine. NCT01595386 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.