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NCT01591655 · ClinicalTrials.gov registry record · Phase 3

Mapracorat Ophthalmic Suspension, 3% for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery

A Phase 3 study, sponsored by Bausch & Lomb Incorporated.

Completed
Registry status
Phase 3
Development phase
360
Enrollment target

NCT01591655: Completed Phase 3 study, sponsored by Bausch & Lomb Incorporated.

NCT01591655 is a Phase 3 study that has completed, run by Bausch & Lomb Incorporated. The registered enrollment target is 360 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (53% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01591655, a Phase 3 study, has completed, sponsored by Bausch & Lomb Incorporated.

COMPLETED
Registry status
Phase 3
Development phase
360 participants
Enrollment target

Study Summary

The objective of this clinical study is to compare the safety and efficacy of mapracorat ophthalmic suspension, 3% with its vehicle for the treatment of postoperative inflammation and pain following cataract surgery. Participants from the United States and Canada will be recruited for this study.

Primary Outcome

Anterior chamber (AC) cells were assessed using a 0 to 4 grading scale by an ophthalmologist using slip lamp biomicroscopy. A slit lamp examination of the lids, conjunctiva, limbus, cornea, anterior chamber, vitreous, and lens was performed without pupil dilation. Accumulation of white blood cells in aqueous was assessed. The grades were defined as: 0 = No cells seen; 1 = 1 - 5 cells; 2 = 6 - 15 cells; 3 = 16 - 30 cells; 4 = \>30 cells. Complete resolution of AC cells was defined as Grade 0.

Interventions

  • DRUG Vehicle
  • DRUG Mapracorat

Trial Details

FieldValue
Enrollment Target 360 participants
Start Date 2012-07
Est. Completion 2013-10
Phase Phase 3
Bausch & Lomb Incorporated

174 total trials

What the finished NCT01591655 record still lists

NCT01591655 is an interventional study that assigns participants to a tested intervention. The registered 360 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (53% lower).

The record links to 0 conditions, and to 2 interventions - of which Vehicle is the first listed.

NCT01591655 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01591655 about?

NCT01591655 is a clinical study titled "Mapracorat Ophthalmic Suspension, 3% for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery". The objective of this clinical study is to compare the safety and efficacy of mapracorat ophthalmic suspension, 3% with its vehicle for the treatment of postoperative inflammation and pain following cataract surgery. Participants from the United States and Canada will be recruited for this study.

What is the current status of trial NCT01591655?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 360 participants. The study started on 2012-07. Estimated completion is 2013-10.

What interventions are being tested in trial NCT01591655?

The interventions under investigation include: Vehicle (DRUG), Mapracorat (DRUG).

Who is sponsoring clinical trial NCT01591655?

This trial is sponsored by Bausch & Lomb Incorporated, which has 174 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01591655's enrollment target sits among peer trials

360 1008th of 2000 higher than 980 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01591655, the US trial registry maintained by the National Library of Medicine. NCT01591655 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.