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NCT01591174 · ClinicalTrials.gov registry record
Ghrelin and Gastric Emptying in Children With Functional Dyspepsia
A clinical trial, sponsored by Children's Mercy Hospital Kansas City.
- Completed
- Registry status
- 30
- Enrollment target
NCT01591174: Completed study, sponsored by Children's Mercy Hospital Kansas City.
NCT01591174 is a clinical trial that has completed, run by Children's Mercy Hospital Kansas City. The registered enrollment target is 30 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01591174 has completed, sponsored by Children's Mercy Hospital Kansas City.
- COMPLETED
- Registry status
- 30 participants
- Enrollment target
Study Summary
The purpose of this research is to see if there are differences between children who have FD and children without FD in the ability of the stomach to empty food and/or in ghrelin hormone levels before and after eating. Chronic abdominal pain is the most common persistent pain condition in children and adolescents. One of the most often diagnosed types of abdominal pain is functional dyspepsia (FD). FD is abdominal pain or discomfort (e.g., nausea, bloating) in the upper abdomen that does not get better by having a bowel movement. One possible explanation for having FD is a delay in the emptying of food from the stomach, or delayed gastric (stomach) emptying. Failing to empty the stomach quickly enough may result in the feeling of being full and cause symptoms of bloating, nausea, vomiting and pain. Further, hormonal changes occur before, during, or after eating food that appear to impact stomach emptying. One of the hormones that changes with meals is called ghrelin. The relationship between ghrelin and stomach emptying needs to be explored more in children with FD. Better understanding of what causes FD symptoms may help us to improve treatment for this condition.
Primary Outcome
Blood samples will be compared pre/post test meal for FD cohorts (EPS/PDS), controls: 0 time/baseline; 6 times/post meal. Associations between relationship of plasma ghrelin type's (acyl and desacyl) pre and postprandial levels \& gastric emptying studied.C-13 acetate to be given and amount of 13CO2 determined for each time point (1 pre/ 14 post meal) using equation nested in software package with UBit IR-300 spectrometer. The concentration of 13CO2 and 12CO2 in the exhaled breath samples to be
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2012-05 |
| Est. Completion | 2016-04-22 |
What the finished NCT01591174 record still lists
NCT01591174 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 30 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT01591174 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01591174 about?
NCT01591174 is a clinical study titled "Ghrelin and Gastric Emptying in Children With Functional Dyspepsia". The purpose of this research is to see if there are differences between children who have FD and children without FD in the ability of the stomach to empty food and/or in ghrelin hormone levels before and after eating. Chronic abdominal pain is the most common persistent pain condition in children ...
What is the current status of trial NCT01591174?
This trial is currently completed. The enrollment target is 30 participants. The study started on 2012-05. Estimated completion is 2016-04-22.
Who is sponsoring clinical trial NCT01591174?
This trial is sponsored by Children's Mercy Hospital Kansas City, which has 184 total clinical trials registered on ClinicalTrials.gov.
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