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NCT01590459 · ClinicalTrials.gov registry record · Phase 2

24-week Study With Open Label Extension of VX-509, an Oral JAK3 Inhibitor, in Subjects Taking Methotrexate

A Phase 2 study, sponsored by Vertex Pharmaceuticals Incorporated.

Completed
Registry status
Phase 2
Development phase
359
Enrollment target

NCT01590459 is a Phase 2 study that has completed, run by Vertex Pharmaceuticals Incorporated. The registered enrollment target is 359 participants.

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The verdict

NCT01590459, a Phase 2 study, has completed, sponsored by Vertex Pharmaceuticals Incorporated.

COMPLETED
Registry status
Phase 2
Development phase
359 participants
Enrollment target

Study Summary

This study is designed to evaluate the safety and efficacy of VX-509, an oral JAK3 inhibitor, for treatment of subjects with active RA who have had an inadequate response to Methotrexate.

Interventions

  • DRUG VX-509
  • DRUG VX-509 matching placebo

Trial Details

FieldValue
Enrollment Target 359 participants
Start Date 2012-04
Est. Completion 2014-07
Phase Phase 2

Sponsor

Vertex Pharmaceuticals Incorporated

191 total trials

What the Registry Record Tells You About NCT01590459

The ClinicalTrials.gov registry entry for NCT01590459 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 359 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Vertex Pharmaceuticals Incorporated, which has 191 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which VX-509 is the first listed.

NCT01590459 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01590459 about?

NCT01590459 is a clinical study titled "24-week Study With Open Label Extension of VX-509, an Oral JAK3 Inhibitor, in Subjects Taking Methotrexate". This study is designed to evaluate the safety and efficacy of VX-509, an oral JAK3 inhibitor, for treatment of subjects with active RA who have had an inadequate response to Methotrexate.

What is the current status of trial NCT01590459?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 359 participants. The study started on 2012-04. Estimated completion is 2014-07.

What interventions are being tested in trial NCT01590459?

The interventions under investigation include: VX-509 (DRUG), VX-509 matching placebo (DRUG).

Who is sponsoring clinical trial NCT01590459?

This trial is sponsored by Vertex Pharmaceuticals Incorporated, which has 191 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.