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NCT01589926 · ClinicalTrials.gov registry record · NA
Bi-Level Positive Airway Ventilation for Acute Chest Syndrome
A NA study, sponsored by Albert Einstein College of Medicine.
- Terminated
- Registry status
- NA
- Development phase
- 3
- Enrollment target
NCT01589926: Clinical Trial NA study, sponsored by Albert Einstein College of Medicine.
NCT01589926 is a NA study that was terminated before completion, run by Albert Einstein College of Medicine. The registered enrollment target is 3 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01589926, a NA study, was terminated before completion, sponsored by Albert Einstein College of Medicine.
- TERMINATED
- Registry status
- NA
- Development phase
- 3 participants
- Enrollment target
Study Summary
Acute chest syndrome (ACS) is a frequent complication of sickle cell disease and is diagnosed by having findings on a chest x-ray and one of the following: chest pain, fever, or trouble breathing. Patients with Acute Chest Syndrome can get very sick and require an exchange transfusion (special large blood transfusion) and mechanical ventilation. Bi-level Positive Airway Pressure (also known as BLPAP or BiPAP) is a device that blows air into a patients lungs via a mask that covers the nose. The goal of this study is to determine whether giving children BiPAP when they have ACS, in addition to providing standard clinical care for ACS, alters the clinical course of these patients. The investigators hypothesize that patients receiving effective BiPAP will have milder clinical courses resulting in shorter hospital stays and fewer transfers to the intensive care unit and exchange transfusions.
Primary Outcome
Length of stay as measured by the time from initial diagnosis of ACS until meeting discharge criteria. It is anticipated length of stay will correlate to efficacy of treatment: shorter stay is theorized to indicate more efficient treatment.
Interventions
- DEVICE Sham CPAP
- DEVICE Bi-level positive airway pressure device
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3 participants |
| Start Date | 2012-07 |
| Est. Completion | 2016-09-08 |
| Phase | NA |
Why NCT01589926 stopped before completion
NCT01589926 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 3 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 2 interventions - of which Sham CPAP is the first listed.
NCT01589926 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01589926 about?
NCT01589926 is a clinical study titled "Bi-Level Positive Airway Ventilation for Acute Chest Syndrome". Acute chest syndrome (ACS) is a frequent complication of sickle cell disease and is diagnosed by having findings on a chest x-ray and one of the following: chest pain, fever, or trouble breathing. Patients with Acute Chest Syndrome can get very sick and require an exchange transfusion (special large...
What is the current status of trial NCT01589926?
This trial is currently terminated. It is a NA study. The enrollment target is 3 participants. The study started on 2012-07. Estimated completion is 2016-09-08.
What interventions are being tested in trial NCT01589926?
The interventions under investigation include: Sham CPAP (DEVICE), Bi-level positive airway pressure device (DEVICE).
Who is sponsoring clinical trial NCT01589926?
This trial is sponsored by Albert Einstein College of Medicine, which has 175 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01589926's enrollment target sits among peer trials
3 1996th of 2000 higher than 4 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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