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NCT01588717 · ClinicalTrials.gov registry record · Phase 1
Excessive Sweating Caused by Antidepressants: Measurement and Treatment With Glycopyrrolate (AIDES-G)
A Phase 1 study, sponsored by Thomas Jefferson University.
- Terminated
- Registry status
- Phase 1
- Development phase
- 5
- Enrollment target
NCT01588717: Clinical Trial Phase 1 study, sponsored by Thomas Jefferson University.
NCT01588717 is a Phase 1 study that was terminated before completion, run by Thomas Jefferson University. The registered enrollment target is 5 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01588717, a Phase 1 study, was terminated before completion, sponsored by Thomas Jefferson University.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 5 participants
- Enrollment target
Study Summary
The study consists of measurement of antidepressant-induced excessive sweating and its treatment with an experimental medication, glycopyrrolate (approved to treat ulcers), which will be added to the antidepressant. This is an open-label study (no placebo group or concealment of the nature of the treatment) that will last 8 weeks, including two weeks of baseline measurement without treatment with the study medication followed by six weeks of treatment with the study medication. The study is pilot study by Dr. Rajnish Mago that is based on the hypothesis that glycopyrrolate will be effective in reducing the severity of excessive sweating caused by antidepressant treatment, and will have minimal side-effects.
Primary Outcome
The main comparison will be the end-of-study mean v. the baseline mean
Interventions
- DRUG Glycopyrrolate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5 participants |
| Start Date | 2012-04 |
| Est. Completion | 2016-06 |
| Phase | Phase 1 |
Why NCT01588717 stopped before completion
NCT01588717 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 5 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (92% lower).
The record links to 0 conditions, and to 1 intervention - of which Glycopyrrolate is the first listed.
NCT01588717 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01588717 about?
NCT01588717 is a clinical study titled "Excessive Sweating Caused by Antidepressants: Measurement and Treatment With Glycopyrrolate (AIDES-G)". The study consists of measurement of antidepressant-induced excessive sweating and its treatment with an experimental medication, glycopyrrolate (approved to treat ulcers), which will be added to the antidepressant. This is an open-label study (no placebo group or concealment of the nature of the tr...
What is the current status of trial NCT01588717?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 5 participants. The study started on 2012-04. Estimated completion is 2016-06.
What interventions are being tested in trial NCT01588717?
The interventions under investigation include: Glycopyrrolate (DRUG).
Who is sponsoring clinical trial NCT01588717?
This trial is sponsored by Thomas Jefferson University, which has 292 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01588717's enrollment target sits among peer trials
5 1989th of 2000 higher than 6 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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