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NCT01581411 · ClinicalTrials.gov registry record · Phase 1
Intra-arterial Thrombolysis for Severe Recent Central Retinal Vein Occlusion
A Phase 1 study, sponsored by Weill Medical College of Cornell University.
- Completed
- Registry status
- Phase 1
- Development phase
- 1
- Enrollment target
NCT01581411: Completed Phase 1 study, sponsored by Weill Medical College of Cornell University.
NCT01581411 is a Phase 1 study that has completed, run by Weill Medical College of Cornell University. The registered enrollment target is 1 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01581411, a Phase 1 study, has completed, sponsored by Weill Medical College of Cornell University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 1 participants
- Enrollment target
Study Summary
Central retinal vein occlusion (CRVO) is a common cause of vision loss, typically affecting individuals during the fifth through seventh decade of life. Eyes with severe CRVO have a poor visual prognosis because current treatments address only secondary complications of CRVO without treating its cause. Intra-ophthalmic artery injection of a small dose of t-PA (clot busting medicine), also called intra-ophthalmic artery thrombolysis, may reopen the central retinal vein-and address the cause of the disease- without exposing the subject to the risks of systemic thrombolysis. Our project aims to evaluate the safety and efficacy of intra-ophthalmic artery thrombolysis in subjects with CRVO.
Interventions
- DRUG Tissue Plasminogen Activator
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1 participants |
| Start Date | 2012-01 |
| Est. Completion | 2015-11 |
| Phase | Phase 1 |
What the finished NCT01581411 record still lists
NCT01581411 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 1 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 1 intervention - of which Tissue Plasminogen Activator is the first listed.
NCT01581411 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01581411 about?
NCT01581411 is a clinical study titled "Intra-arterial Thrombolysis for Severe Recent Central Retinal Vein Occlusion". Central retinal vein occlusion (CRVO) is a common cause of vision loss, typically affecting individuals during the fifth through seventh decade of life. Eyes with severe CRVO have a poor visual prognosis because current treatments address only secondary complications of CRVO without treating its cau...
What is the current status of trial NCT01581411?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 1 participants. The study started on 2012-01. Estimated completion is 2015-11.
What interventions are being tested in trial NCT01581411?
The interventions under investigation include: Tissue Plasminogen Activator (DRUG).
Who is sponsoring clinical trial NCT01581411?
This trial is sponsored by Weill Medical College of Cornell University, which has 701 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01581411's enrollment target sits among peer trials
1 2001st of 2000 the lowest of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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