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NCT01580423 · ClinicalTrials.gov registry record · NA
The Role of Substance P on Perception of Breathlessness During Resistive Load Breathing
A NA study, sponsored by Dartmouth-Hitchcock Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 16
- Enrollment target
NCT01580423 is a NA study that has completed, run by Dartmouth-Hitchcock Medical Center. The registered enrollment target is 16 participants.
The verdict
NCT01580423, a NA study, has completed, sponsored by Dartmouth-Hitchcock Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 16 participants
- Enrollment target
Study Summary
Substance P is released from sensory nerves and transmits pain information into the central nervous system. As pain and dyspnea share many characteristics, including similar neurological pathways, it is possible that substance P may contribute to the sensation of dyspnea. The hypothesis of the study is that patients with chronic obstructive pulmonary disease (COPD) will provide lower ratings of breathlessness during resistive load breathing with oral aprepitant, a medication that blocks the activity of substance P, compared with placebo.
Interventions
- DRUG placebo
- DRUG aprepitant
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2012-04 |
| Est. Completion | 2013-03 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01580423
The ClinicalTrials.gov registry entry for NCT01580423 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 16 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Dartmouth-Hitchcock Medical Center, which has 427 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which placebo is the first listed.
NCT01580423 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01580423 about?
NCT01580423 is a clinical study titled "The Role of Substance P on Perception of Breathlessness During Resistive Load Breathing". Substance P is released from sensory nerves and transmits pain information into the central nervous system. As pain and dyspnea share many characteristics, including similar neurological pathways, it is possible that substance P may contribute to the sensation of dyspnea. The hypothesis of the study...
What is the current status of trial NCT01580423?
This trial is currently completed. It is a NA study. The enrollment target is 16 participants. The study started on 2012-04. Estimated completion is 2013-03.
What interventions are being tested in trial NCT01580423?
The interventions under investigation include: placebo (DRUG), aprepitant (DRUG).
Who is sponsoring clinical trial NCT01580423?
This trial is sponsored by Dartmouth-Hitchcock Medical Center, which has 427 total clinical trials registered on ClinicalTrials.gov.
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