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NCT01567839 · ClinicalTrials.gov registry record · Phase 4
Testing the Anesthetic Effectiveness of Three Different Dental Local Anesthetics Injected Next to a Lower First Molar
A Phase 4 study, sponsored by Ohio State University.
- Completed
- Registry status
- Phase 4
- Development phase
- 60
- Enrollment target
NCT01567839: Completed Phase 4 study, sponsored by Ohio State University.
NCT01567839 is a Phase 4 study that has completed, run by Ohio State University. The registered enrollment target is 60 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (88% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01567839, a Phase 4 study, has completed, sponsored by Ohio State University.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 60 participants
- Enrollment target
Study Summary
Infiltration (injecting next to the tooth) injections are common in dentistry and a number of studies have shown that articaine anesthetic, when injected next to the tooth as a supplemental injection, works very well following a typical inferior alveolar (lower jaw) nerve block. No study has compared 4% articaine with 1:100,000 epinephrine, 4% prilocaine with 1:200,000 epinephrine, and 4% lidocaine with 1:100,000 epinephrine in mandibular (lower jaw) infiltration injections of the first molar. The purpose of this prospective, randomized, double-blind, crossover study is to compare the degree of anesthesia obtained from the three solutions as a primary infiltration injection next to the mandibular first molar. The investigators also will record the pain of injection and postoperative pain.
Primary Outcome
Two consecutive 80/80 readings (no patient response) during 60 minutes of testing with an electric pulp tester.
Interventions
- PROCEDURE Mandibular buccal Infiltration injection
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2012-05 |
| Est. Completion | 2013-05 |
| Phase | Phase 4 |
What the finished NCT01567839 record still lists
NCT01567839 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (88% lower).
The record links to 0 conditions, and to 1 intervention - of which Mandibular buccal Infiltration injection is the first listed.
NCT01567839 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01567839 about?
NCT01567839 is a clinical study titled "Testing the Anesthetic Effectiveness of Three Different Dental Local Anesthetics Injected Next to a Lower First Molar". Infiltration (injecting next to the tooth) injections are common in dentistry and a number of studies have shown that articaine anesthetic, when injected next to the tooth as a supplemental injection, works very well following a typical inferior alveolar (lower jaw) nerve block. No study has compare...
What is the current status of trial NCT01567839?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 60 participants. The study started on 2012-05. Estimated completion is 2013-05.
What interventions are being tested in trial NCT01567839?
The interventions under investigation include: Mandibular buccal Infiltration injection (PROCEDURE).
Who is sponsoring clinical trial NCT01567839?
This trial is sponsored by Ohio State University, which has 552 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01567839's enrollment target sits among peer trials
60 1125th of 2000 higher than 799 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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